What is s known about changes in microvillar fusion domain arrangement upon gamete plasma membrane contact.?
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Changes in microvillar fusion domain arrangement upon gamete plasma membrane contact have been studied in several papers. It has been shown that the oocyte membrane has two distinct areas, one rich in microvilli and the other without microvilli . These two regions have different mechanical and adhesive properties, and both are distributed over the entire oocyte surface . The presence of two types of membrane domains with different properties suggests that there are different mechanisms involved in the fusion process . In addition, studies with hamster gametes have shown that the microvilli of the vitellus wrap around the head of the sperm and fuse with its plasma membrane . This is in contrast to gamete fusion in marine invertebrates, where initial contact with the egg membranes is made by an apical process extending from the inner acrosomal membrane . These findings suggest that the arrangement of microvillar fusion domains may vary between different species and may play a role in the specific mechanisms of gamete fusion.
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