What is the Frank Banghart model?
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The Frank Banghart model is a kinetic model that describes the transformation of an almost racemic system into a homochiral system. It assumes an autocatalytic reaction where enantiomers are formed from an achiral substrate, and an interaction between the enantiomers that eliminates one another. Originally, both steps were assumed to be irreversible, but a modified version of the model allows for the first step to be reversible. The modified Frank model (MFM) can exhibit three distinct time-evolutions: one where both enantiomers completely disappear, another leading to complete monochirality, and a third resulting in a racemic final state. The conditions for each direction of evolution depend on the relative magnitudes of rate constants and are independent of the initial composition .
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