What is the impact of IQOS iluma smoking on lung health?
Best insight from top research papers
IQOS smoking, including dual exposure with cigarette smoke, has detrimental effects on lung health. Studies show that IQOS exposure induces oxidative stress, mitochondrial dysfunction, and epithelial-mesenchymal transition (EMT) signaling, leading to small airway fibrosis . Additionally, chronic inhalation of IQOS aerosols in mice results in lung damage, inflammation, and immune cell recruitment similar to that caused by cigarette smoke exposure, indicating potential lung function impairment . Furthermore, IQOS exposure leads to suppressed weight gain, increased serum cotinine levels, and apoptosis-related pathways activation, ultimately inducing pulmonary emphysema . Despite being marketed as a safer alternative, IQOS ads with modified risk tobacco product claims can influence perceptions of harm and exposure, impacting both smokers and potentially physicians .
Answers from top 5 papers
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| Papers (5) | Insight |
|---|---|
| Chronic exposure to IQOS aerosol induces pulmonary emphysema through apoptosis-related pathways, suggesting that IQOS smoking negatively impacts lung health by promoting cell death. | |
| Not addressed in the paper. | |
9 Citations | Short-term inhalation of IQOS aerosols induces lung damage, inflammatory immune-cell accumulation, and proinflammatory changes similar to cigarette smoke exposure, potentially impairing lung function. |
| Dual exposure to IQOS and cigarette smoke can lead to increased oxidative stress, mitochondrial dysfunction, and activation of pathogenic signaling, potentially harming lung health and exacerbating respiratory diseases. | |
| Not addressed in the paper. |
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