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What is the medicinal treatment of ovarian cancer? 


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The medicinal treatment of ovarian cancer includes a combination of cytoreductive surgery, platinum-based chemotherapy, targeted therapies, and immunotherapy . Platinum-based chemotherapy drugs such as cisplatin, carboplatin, paclitaxel, and docetaxel are commonly used in combination therapy . Targeted therapies aim to selectively target molecules and mechanisms that cause chemoresistance, such as efflux pump inhibitors, tyrosine kinase inhibitors, and PARP inhibitors like olaparib . Immunotherapy, particularly immune checkpoint inhibitors, is being investigated in combination with chemotherapy, anti-angiogenetics, PARP inhibitors, and radiotherapy . The use of poly ADP-ribose polymerase (PARP) inhibitors, bevacizumab, and drugs targeting homologous recombination deficiency is becoming more common in the treatment of ovarian cancer . Overall, a comprehensive approach involving surgery, chemotherapy, targeted therapies, and immunotherapy is necessary for the effective treatment of ovarian cancer.

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Open accessJournal ArticleDOI
09 Nov 2020-BMJ
255 Citations
The paper discusses the treatment of ovarian cancer, including surgical cytoreduction followed by adjuvant chemotherapy. It also mentions the use of maintenance therapy with poly ADP-ribose polymerase inhibitors, bevacizumab, and drugs targeting homologous recombination deficiency.
The paper discusses the treatment of ovarian cancer, which includes surgical removal of the tumor mass followed by chemotherapy, hormone therapy, and/or radiotherapy.
The medicinal treatment of ovarian cancer includes cytoreductive surgery, platinum-based chemotherapy, and targeted therapies such as PARP inhibitors and immune checkpoint inhibitors.
The medicinal treatment of ovarian cancer mentioned in the paper is a pharmaceutical composition comprising olaparib and Plasticines alkaloid compounds.

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What are the different types of surgery for ovarian cancer?5 answersSurgery for ovarian cancer includes various procedures such as opportunistic salpingectomy, peritoneal cytoreductive surgery, lymph node dissections, tumor debulking, and intestinal resection. Opportunistic salpingectomy involves the removal of the fallopian tubes during other surgeries like hysterectomy. Peritoneal cytoreductive surgery aims to reduce the tumor burden in the peritoneal cavity. Lymph node dissections are performed to determine the extent of the disease and its prognosis. Tumor debulking is a procedure that aims to achieve maximal cytoreduction, ideally with no residual disease, to enhance the effectiveness of subsequent chemotherapy. Intestinal resection may be necessary during cytoreductive surgery for ovarian cancer, particularly when there are metastases involving the bowel. Other procedures such as cholecystectomy, porta hepatis debulking, and omental bursectomy may also be performed for advanced ovarian cancer involving the upper abdomen.

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