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What is the molecular property of Uracil? 


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Uracil is a base that can coordinate with transition metal cations through its nitrogen atoms and carbonyl oxygens. It has the ability to form bidentate complexes with metal ions, with the O(4) and N(3) sites being favorable for cation binding. In some cases, uracil derivatives can also act as unidentate ligands, with O(4) or N(1),N(3) being involved in cation binding. The coordination tendency of uracil and its derivatives has been studied in the context of their biological uses and the formation of metal complexes. These complexes have shown significant biological activities.

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Uracil is a nucleobase that is one of the four bases found in RNA.
The molecular property of Uracil is that it consists of a sulfated uracil and a family of molecules based upon the structure.
Uracil is a nucleating agent and rheological modifier for the copolymer P3HB4HB.

Related Questions

Why is uracil only in rna?5 answersUracil is exclusively found in RNA due to its role as a key distinctive constituent in RNA nucleotides, unlike DNA which contains thymine instead of uracil. The presence of uracil in RNA allows it to form base pairs with adenine, similar to thymine in DNA, contributing to RNA's structural and functional diversity. Uracil's incorporation into DNA can lead to instability and affect cellular functions, necessitating repair mechanisms to remove uracil from DNA to prevent gene drift. Additionally, uracil has been implicated in various physiological and pathological processes, highlighting its significance in cellular processes and genomic studies. Overall, the unique presence of uracil in RNA underscores its essential role in RNA structure, function, and biological processes.
What gets degraded to uracil in muscle?5 answersUracil in muscle can arise from the misincorporation of dUMP instead of dTMP during DNA replication or from cytosine deamination. The removal of uracil from DNA in muscle tissue primarily involves the action of DNA glycosylases, with UNG being the most significant enzyme in removing uracil from U:A pairs and single-stranded DNA. In non-proliferative tissues like muscle, both UNG and SMUG1 contribute similarly to the removal of uracil from a U:G context. Additionally, the presence of uracil in DNA can lead to genome instability and mutations, making its removal crucial for maintaining genomic integrity. The process of uracil removal involves specific repair pathways, such as base excision repair, to prevent the accumulation of mutagenic uracil residues in muscle tissue.
What is molecular characterization?4 answersMolecular characterization is the process of characterizing an organism at the molecular level, without considering the effects of the environment, development, or physiological state of the organism. It involves the use of molecular techniques, such as DNA sequencing and PCR, to identify and characterize organisms. This method is faster and more efficient compared to traditional morphological characterization methods. Molecular characterization can be used to identify and track pathogens associated with food, ensuring food safety. It can also be used to understand the structure and properties of polymer networks, allowing for molecular-level control over material properties. Additionally, molecular characterization can be used to predict protein affinity and obtain new biological information. Overall, molecular characterization plays a crucial role in various fields, including microbiology, food safety, and materials science.
What is the structural property of Uracil?3 answersUracil is a base with the ability to coordinate to metal ions through its nitrogen atoms and carbonyl oxygens. It has a tendency to form bidentate complexes with metal cations, with O(4) and N(3) being the favorable binding sites. In some cases, uracil derivatives can also act as unidentate ligands, with O(4) or N(1),N(3) being involved in binding. The involvement of different atoms in coordination depends on the specific metal ion and uracil derivative. These metal complexes of uracil and its derivatives have shown significant biological activities.Additionally, uracil has the ability to form aggregates, which plays a role in initiating structure formation. This property has been utilized to create nanostructured layers for antireflection coatings, demonstrating broadband and wide-angle antireflection performance.In aqueous solution, uracil can form complexes with water molecules through hydrogen bonding. The structure of these complexes and the hydrogen bridge parameters explain the low solubility of uracil in water at room temperature.
How uracil moeity undergo bioransformation in human?5 answersUracil in DNA can be generated by cytosine deamination or dUMP misincorporation. It is highly enriched at the centromere of the human genome and is preferentially localized within the binding regions of the centromere-specific histone CENP-A. Human centromeric DNA contains a higher level of uracil, and uracil-DNA glycosylase UNG can excise centromeric uracil. Uracil residues in DNA are removed by specific uracil-DNA glycosylases in the base excision repair (BER) pathway. The major human AP endonuclease 1, APE1, can cleave oligonucleotide duplexes containing a single U•G base pair, suggesting a backup pathway to BER to remove uracils arising from cytosine deamination. Uracil processing in B cells involves base removal by uracil DNA glycosylase (UNG) and detection by the mismatch repair (MMR) complex MSH2/6. Uracil in DNA is removed by uracil-DNA glycosylase, including UNG2 and SMUG1, and is also introduced into retroviral DNA by the host as part of a defense mechanism. The uracil-DNA repair pathway is highly conserved in organisms, including E. coli and human cells.
What are the specific phytochemical compounds found in Agor and their individual properties and applications?2 answersGarcinia indica (kokum) contains various bioactive compounds including garcinol, hydroxycitric acid, and anthocyanins (cyanidin-3-glucoside and cyanidin-3-sambubioside). Brazil has a diverse flora with potential for the discovery of new molecules with scientific, economic, and social interest. Anchusa strigosa contains phenolic acids, flavonoids, alkaloids, sterols, and terpenoids. The phytochemical compounds found in Agor are not mentioned in the provided abstracts.

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