What is the effect of glycerol mono stearate on rheology of hydroxypropyl cellulose solution?5 answersThe effect of glycerol on the rheology of hydroxypropyl cellulose (HPC) solutions has been extensively studied. Glycerol, at concentrations between 3% and 5%, increases the viscosity of HPC polymer dispersions without altering their rheological behavior. Additionally, interactions between HPC and surfactants like sodium laurylsulfate (SDS) can modify the physicochemical properties of the system. In HPC-SDS solutions, viscosity changes are dependent on the HPC-SDS interaction, with viscosity increasing up to a maximum at specific SDS concentrations before decreasing to a constant value. Furthermore, the phase behavior of HPC in mixed solvents of glycerol and water has been investigated, highlighting the molecular processes of phase separation and the temperature-dependent chain rigidity of HPC.
What is the optimal concentration range for hydroxpropylcellulose in pellet formulations to maintain plasticity and produce spherical pellets?5 answersThe optimal concentration range for hydroxypropyl cellulose (HPC) in pellet formulations to maintain plasticity and produce spherical pellets is crucial for pharmaceutical applications. Research indicates that for fiber formation, an optimum concentration range of 38–52% w/w of hydroxypropyl cellulose gels is essential. Additionally, the physicochemical properties of HPC derived from Betung bamboo showed promising characteristics for tablet formulation, suggesting its potential in maintaining plasticity and forming tablets. Furthermore, studies on HPC interactions with celecoxib highlighted the importance of understanding drug-polymer interactions for formulation development, emphasizing the role of different HPC grades in sustaining drug supersaturation and solubilization. By considering these findings, a concentration range within 38–52% w/w of HPC could be optimal for maintaining plasticity and producing spherical pellets in pellet formulations.
What are the different uses of glycerin?4 answersGlycerin, also known as glycerol, has various uses. It is commonly used in the production of soaps, cosmetics, pharmaceuticals, and food products. Glycerin is also used as an energy source in poultry diets, with positive responses observed in studies. In addition, glycerin can be used in animal feeding, specifically in ruminant diets, without causing any negative effects on ruminal organic matter degradation, pH, ammonia levels, and microbial protein production. Glycerol is used to protect proteins during storage and enhance their solubility in cryocrystallography. It is also used in the sterilization of pharmaceutical formulations, with sterile filtration being the preferred method. Furthermore, glycerol has been found to regulate cardiac metabolism and reduce myocardial β-oxidation of fatty acids for cardiac cytoprotection.
What are the important characteristics in glycerin that helps in bioplastic?5 answersGlycerin has important characteristics that contribute to its use in bioplastics. It has been found that the addition of glycerin to plasticized doughs can improve elasticity at small deformations and extensional deformational stress at large deformations. Glycerin also improves the moisture barrier properties of soy protein isolate (SPI) films, making them more suitable for potential packaging applications. In addition, glycerin has been shown to be an effective plasticizer for AP/HTPB propellant, improving its burning characteristics, mechanical properties, and processability. These findings highlight the versatility of glycerin as a plasticizer in different applications, where it can enhance the performance and functionality of bioplastics.
What is properties of glycerol in hydrogel?2 answersGlycerol has several properties in hydrogels. It can improve the mechanical properties of hydrogels, such as tensile strength and elongation at break. Glycerol also enhances the water absorption rate, swelling rate, capillary water absorption capacity, and permeability of hydrogels. Additionally, glycerol can improve the effective crosslinking density of hydrogels. It also contributes to the antifreeze and moisturizing properties of hydrogels. Furthermore, glycerol allows hydrogels to have self-healing ability. Glycerol is also known to provide good lubricating properties for hydrogels under dry friction. Finally, glycerol has been shown to have excellent biocompatibility and does not cause any toxic effects on cells.
How does glycerol affect the properties of a cellulose based bioplastic?5 answersGlycerol has been found to have a significant effect on the properties of cellulose-based bioplastics. The addition of glycerol as a plasticizer to cellulose films increases their tensile strength and elongation at break, resulting in improved flexibility and mechanical properties. However, the effect of glycerol on cellulose acetate (CA) films varies depending on the purpose of application. The addition of glycerol into CA films increases thickness, opacity, and water vapor permeability, while films plasticized with triethyl citrate (TEC) exhibit opposite behavior. Glycerol also plays a crucial role in enhancing the biodegradability of bioplastics. The application of glycerol as a plasticizer in carrageenan waste cellulose bioplastics significantly improves their ability to biodegrade, with the highest value observed at a concentration of 5-7%. Additionally, glycerol can be used as a renewable carbon source to produce bacterial cellulose (BC) through more efficient and environmentally friendly bioprocesses, reducing the costs associated with BC production. Overall, glycerol has a positive impact on the properties of cellulose-based bioplastics, improving their mechanical properties, biodegradability, and production efficiency.