What is the phenotype of Gld2 KO mice?
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Gld2 knockout (KO) mice show detectable alterations in specific miRNA monoadenylation in the hippocampus compared to wild type, but these modifications do not produce any detectable effect on miRNA stability. Additionally, there is no overt change in animal behavior when comparing Gld2 KO to wild-type mice. These findings suggest that miRNA monoadenylation-mediated stability is cell type-specific and that monoadenylation has no measurable effect on higher cognitive function .
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| Papers (4) | Insight |
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| The provided paper is about mice lacking DGKε, not Gld2. Therefore, there is no information about the phenotype of Gld2 KO mice in this paper. | |
28 Citations | The phenotype of GluK2 KO mice includes reduced locomotor activity, impaired sociability, enhanced spatial learning, and impaired spatial reversal learning. |
13 Citations | The provided paper does not mention anything about Gld2 KO mice. |
3 Citations | The paper does not mention any unique phenotype in GLO-2 KO mice under baseline conditions. |
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