What is the relationship between gender dysphoria and congenital adrenal hyperplasia (CAH)?
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Gender dysphoria and congenital adrenal hyperplasia (CAH) are related conditions. CAH is a group of disorders characterized by enzymatic defects in cortisol biosynthesis, and it can lead to gender dysphoria in some patients . The frequency of gender dysphoria among 46,XX CAH patients is not well-known, but it has been reported to be around 9% in late adolescence/adulthood . Female-raised patients with CAH frequently report the desire to be male and adopt male-typical behavior, but this does not necessarily correspond to gender dysphoria . However, male-raised CAH patients have a higher proportion of gender dysphoria compared to female-raised patients . Gender dysphoria in CAH patients may present as both male to female and female to male gender dysphoria . It is important to consider genetic and environmental factors, as well as the risk of sexual abuse, when assessing the risk of gender dysphoria in CAH patients .
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22 Jul 2021 | The paper reports two cases of nonclassic CAH in adolescents with gender dysphoria, suggesting a possible relationship between the two conditions. |
01 Jan 2021 1 Citations | The paper does not specifically mention the relationship between gender dysphoria and congenital adrenal hyperplasia (CAH). |
01 Jan 2021 | There is a higher prevalence of gender dysphoria in individuals with CAH, particularly in those with 46,XX karyotype. |
| Gender dysphoria may be developed in 5.2% of CAH patients. | |
21 Citations | The frequency of gender dysphoria (GD) among 46,XX CAH patients is 9% and is more common in those raised as males. |
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