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Why is mcr-9 more commonly reported in Salmonella than mcr-1? 


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mcr-9 is more commonly reported in Salmonella than mcr-1 due to its prevalence in different species of Klebsiella, including K. pneumoniae, K. quasipneumoniae subsp. quasipneumoniae, and K. variicola, making it more widespread across various bacterial strains . Additionally, mcr-9 has been found in Salmonella enterica serovar Indiana and a monophasic variant of S. Typhimurium, indicating its presence in different Salmonella serovars . On the other hand, mcr-1 has been predominantly associated with Escherichia coli and Salmonella, with a lower prevalence rate in Salmonella strains . The genetic events leading to the spread of mcr-9, including its integration and mobilization, have contributed to its transmission between humans and nature, further enhancing its presence in Salmonella .

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Open accessJournal ArticleDOI
Zengfeng Zhang, Xiaorong Tian, Chunlei Shi 
25 Jul 2022-Antibiotics
3 Citations
mcr-9 is more common in Salmonella than mcr-1 possibly due to its higher prevalence (65.2%) compared to mcr-1 (24.4%), as indicated in the global genomic analysis.
mcr-9 is more common in Salmonella due to its presence on IncHI2-ST1 plasmids, enabling spread alongside clinically relevant resistance genes, unlike mcr-1.
Not addressed in the paper.
Not addressed in the paper.

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