Showing papers on "Alveolar hydatid disease published in 2013"
TL;DR: A 43-year-old male presented with clinical features of obstructive jaundice and multiple attempts to obtain tissue diagnosis in the form of USG-guided FNAC & tru-cut biopsy failed, leading to E. multilocularis infection of the liver being considered in the differential diagnosis.
Abstract: A 43-year-old male presented with clinical features of obstructive jaundice. Biochemical tests and radiologic imaging were suggestive of intrahepatic cholangiocarcinoma with hilar block. Multiple attempts to obtain tissue diagnosis in the form of USG-guided FNAC & tru-cut biopsy failed. Exploratory laparotomy and wedge biopsy confirmed E. multilocularis (alveolar hydatid disease). The patient was managed with albendazole therapy. At 8-month follow-up, the patient was clinically asymptomatic with near normalization of biochemical parameters and significant regression of the lesion as shown by computed tomography. E. Multilocularis infection of the liver is quite rare in the Indian subcontinent and poses a diagnostic dilemma. Nonetheless, despite its rarity, it should be considered in the differential diagnosis when a patient presents with clinical and radiological features of a space-occupying lesion of the liver while attempts to set pathological diagnosis by FNA/ tru-cut biopsy are inconclusive. Awareness of this emerging infectious disease could prevent a fatal outcome, particularly amongst patients who have been exposure to wild life.
2 citations
TL;DR: Alveolar echinococcosis is caused by the cestode parasite, Echinococcus multilocularis, and is a very serious zoonosis and intermediate hosts are arvicolid rodents, small mammals and, as aberrant hosts, humans.
Abstract: Alveolar echinococcosis (AV), also known as alveolar hydatid disease, is caused by the cestode parasite, Echinococcus multilocularis, and is a very serious zoonosis. Its definitive host is the red fox and intermediate hosts are arvicolid rodents, small mammals and, as aberrant hosts, humans. The pathological features in the intermediate host are related to parasitic growth and to immune response. The epidemiology of this disease is complex because of changing ecological requirements of this parasite and movement of definitive and intermediate hosts.