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Showing papers on "Antiinfective agent published in 1992"



Journal ArticleDOI
01 Jan 1992
TL;DR: Benzyl-trans-4-coumarate and 16-hydroxycarnosic acid were identified as the major in vitro antibacterial and antifungal compounds in Eriodictyon angustifolium and Salvia apiana respectively.
Abstract: Benzyl-trans-4-coumarate (6) and 16-hydroxycarnosic acid (8) were identified as the major in vitro antibacterial and antifungal compounds in Eriodictyon angustifolium and Salvia apiana respectively. These plants were investigated after screening 12 southwestern U.S. herbal remedies for potential antiinfective activity.

11 citations


Journal Article
TL;DR: The ideal strategies for treatment of infectious diseases guided by microbiological diagnosis and resistance pattern are violated in most developing countries, leading to excessive use of antiinfectiva and development of resistance.
Abstract: Widespread use and misuse of antiinfectiva have resulted in a problem of drug resistance linked to treatment of infectious diseases. In developing countries especially, the sale of such drugs is poorly controlled and the pharmaceutical industry is dumping obsolete products. Intensive marketing, lack of diagnostic facilities and receptive local cultural attitudes to new "wonder drugs" such as antibiotics, have resulted in dramatic unnecessary use of such. Therefore the ideal strategies for treatment of infectious diseases guided by microbiological diagnosis and resistance pattern are violated in most developing countries, leading to excessive use of antiinfectiva and development of resistance. This has serious consequences for the infections that cause most cases of infant mortality, namely malaria, diarrhoeas and infections of the respiratory tract. Improvements in this vicious circle of drug use and resistance can only be made by attacking several factors simultaneously. There is a need for general information, stricter legislation, essential drug lists, national drug policies, better knowledge of local resistance patterns, better diagnostic facilities, better knowledge about local beliefs about drugs and better communication to local health workers and the community.

3 citations


Journal ArticleDOI
TL;DR: Principles and practice of infectious diseases, handbook of antimicrobial therapy, 1992, and principles and practice in clinical practice, 1992.
Abstract: Principles and practice of infectious diseases, handbook of antimicrobial therapy, 1992 , Principles and practice of infectious diseases, handbook of antimicrobial therapy, 1992 , کتابخانه دیجیتالی دانشگاه علوم پزشکی و خدمات درمانی شهید بهشتی

1 citations