Showing papers on "ATP transport published in 1979"
TL;DR: The above data indicate that ADP/ATP transport across the mitochondrial membrane is primarily electrogenic, and suggests that the ATP-dependent changes of pH are not characteristic of the mechanism of the ADP-ATP carrier, but correspond to a passive transport of H+.
23 citations
TL;DR: This chapter reviews adenine nucleotide (ADP/ATP) transport across the inner membrane of mitochondria, which is catalyzed by a protein and can be identified by its ability to bind specific inhibitory ligands including atractyloside, carboxyatractylOSide, and bongkrekic acid.
Abstract: Publisher Summary This chapter reviews adenine nucleotide (ADP/ATP) transport across the inner membrane of mitochondria, which is catalyzed by a protein and can be identified by its ability to bind specific inhibitory ligands including atractyloside, carboxyatractyloside, and bongkrekic acid. ADP/ATP transport has been found to occur in mitochondria isolated from a number of sources. The ADP/ATP carrier has been recently characterized in the yeast Saccharomyces cerevisiae by covalent photolabeling with 3 H-labeled photoactivable derivatives of atractyloside and ADP. The mitochondrial protein that is able to recognize specifically atractyloside and that may be the ADP/ATP carrier or a part of the carrier has been recently purified from the yeast Saccharomyces cerevisiae . The atractyloside-binding protein is able to bind covalently, upon photoirradiation, all-labeled photoactivable derivatives of atractyloside and of ADP or ATP. Photolabeling by ADP or ATP derivatives is prevented by preincubation of the mitochondria with atractyloside or carboxyatractyloside, which points to the specificity of the ADP or ATP labeling.
6 citations