Showing papers on "Benzopyrans published in 1971"
Patent•
26 Aug 1971
TL;DR: In this article, the authors present a scheme to select agents from a group of IMMUNO-INFLAMMATORY agents who possess anti-allergic and anti-inflammatory activities.
Abstract: COMPOUNDS OF THE FORMULA: X<(-(R,R2-CYCLOHEX-1-EN-6-ON-1,2-YLENE)-O-) IN WHICH X IS THE MOIETY -CO-C(-R3)=C(-CO-Z)- Z IS A MEMBER SELECTED FROM THE GROUP CNSISTING OF -OR4, -N(-R5)-R6 -CL,-BR, AND-OM; R, R2, R3, R4 AND R5 ARE INDEPENDENTLY SELECTED FROM THE GROUP CONSISTING OF-H, LOWER ALKYL, PHENYL AND BENZYL, R6 IS SELECTED FROM THE GROUP CONSISTING OF-H, LOWER ALKY, PHENYL, BENZYL, LOWER DIALKYLAMINOALKYL AND CYCLOALKYL OF 3 TO 10 CARBON ATOMS, AND WHEN TAKEN WITH R5 AND THE NITROGEN ATOM TO WHICH THEY ARE BONDED FORMS THE MORPHOLINO, PIPERIDINO AND PIPERAZINO GROUPS, AND M IS SELECTED FROM ALKALI METAL CATIONS AND-NH4, ARE IMMUNO-INFLAMMATORY AGENTS POSSESSING ANTIALLERGIC AND ANTIINFLAMMATORY ACTIVITY. THE COMPOUNDS OF THIS INVENTION ARE ALSO INTERMEDIATES FOR THE SYNTHESIS OF KNOWN CHROMONE ND COUMARIN DERIVATIVES.
4 citations