Showing papers on "Canine Mastocytoma published in 1960"
TL;DR: It is suggested that the inability of canine mastocytoma to wheal on physical trauma may be a function of the large number of eosinophils present (their antihistamine content), and that the presence of mast cells in viscera, bone marrow, etc., in mast cell disease (in either species) may reflect an overgrowth ofmast cells present.
Abstract: In previous reports we have presented a general introduction to comparative canine and human dermatology1and discussed mast cell disease in both species.2In the latter report we noted the following: Cystic rarefaction of the ischium, in one of our canine cases, which coincided closely to some reported cases of bone involvement in human urticaria pigmentosa.3 That the inability of canine mastocytoma to wheal on physical trauma may be a function of the large number of eosinophils present (their antihistamine content4). Our attempts to correlate the wheal-inhibiting effect of eosinophils in several cases of human urticaria pigmentosa were inconclusive. This thesis shall be tested in a large series of cases. That the presence of mast cells in viscera, bone marrow, etc., in mast cell disease (in either species) may not be evidence of metastasis, but may reflect an overgrowth of mast cells present
6 citations