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Showing papers on "Controlled release published in 1971"


Patent
A Zaffaroni1
09 Aug 1971
TL;DR: In this paper, a bandage for continuous administration to circulation of controlled quantities of systemically active coronary vasodilators over a prolonged period of time by absorption through the external body skin or mucosa is comprised of a backing member, a pressure-sensitive adhesive coating, and a reservoir containing the drug confined within a wall member.
Abstract: Medical bandage for use in the continuous administration to circulation of controlled quantities of systemically active coronary vasodilators over a prolonged period of time by absorption through the external body skin or mucosa is comprised of a backing member, a pressure-sensitive adhesive coating, and a reservoir containing the drug confined within a wall member. The wall member is formed from drug release rate controlling material to continuously meter the flow of a therapeutically effective amount of the drug from the reservoir to the skin at a controlled and predetermined rate over a period of time.

228 citations




Patent
David A. Hofacker1
08 Nov 1971
TL;DR: The substantially spherical capsules are particularly adapted for containing a liquid and have permeable or semi-permeable capsule walls as mentioned in this paper, and they have the ability to release solutes by an effect resembling osmosis and to release a liquid by a transmission and evaporation mechanism.
Abstract: The disclosed substantially spherical capsules are particularly adapted for containing a liquid and have permeable or semi-permeable capsule walls. The capsule walls can comprise a first crystalline phase, an amorphous phase which ordinarily is intimately associated with the crystalline phase, and, preferably, a dispersed (discontinuous) second crystalline or semi-crystalline phase such as a wax. These capsules have the ability to release a solute by an effect resembling osmosis and to release a liquid by a transmission and evaporation mechanism.

42 citations



Patent
27 Jul 1971
TL;DR: A CONTROLLED RELEASE COATING COMPOSITION COMPRISING an ORGANIC SOLVENT SOLUTION of AN ORGANOPOLYSILOXANE and a SOLVent SOLUBLE POLYMER of a POLYmerIZable UNSATURATED ALIPHATIC DIBASIC ACID or DERIVATIVE THEREOF was presented in this paper.
Abstract: A CONTROLLED RELEASE COATING COMPOSITION COMPRISING AN ORGANIC SOLVENT SOLUTION OF AN ORGANOPOLYSILOXANE AND A SOLVENT SOLUBLE POLYMER OF A POLYMERIZABLE UNSATURATED ALIPHATIC DIBASIC ACID OR DERIVATIVE THEREOF. INCREMENTAL CHANGES IN THE PROPORTION OF SAID SOLVENT SOLUBLE POLYMER LEAD TO INCREMENTAL CHANGES IN THE RELEASE FORCE OF THE COATINGS PRODUCED WITH SUCH COMPOSITIONS. PROCESSES FOR APPLYING THE NEW COATING COMPOSITIONS ARE ALSO DESCRIBED. A TYPICAL COMPOSITION COMPRISES A TOLUENE SOLUTION OF A POLYMETHYLSILOXANE AND A C18 ALKYL VINYL ETHER/MALEIC ANHYDRIDE COPOLYMER IN A 10:1 RATIO ON A WEIGHT BASIS.

15 citations


Patent
15 Jul 1971
TL;DR: In this paper, the walls of the microcapsules are so gas-permeable as to allow controlled release of the active material vapour, have increased activity duration and reduced phytotoxicity.
Abstract: Natural or synthetic plant protection agents and other pesticides, micro-encapsulated in powdered polymers by coacervation techniques so that the walls of the microcapsules are so gas-permeable as to allow controlled release of the active material vapour, have increased activity duration and reduced phytotoxicity.

14 citations


Journal ArticleDOI
TL;DR: In this article, the phenomena accompanying the injection of megavolt electrons into solid dielectrics and the accumulation and release of trapped electric charge are reviewed, and techniques for demonstrating the electrostatic deceleration of injected electrons and for measuring the normal and the induced release of the stored energy are described.

10 citations


Patent
27 Jul 1971
TL;DR: In this article, the authors compare an AQUEOUS EMULSION of a POLYMETHYLSILOXANE and a POLUVINYL METHYL ETHER/MALEIC ANHDRIDE COPOLYMER in a 10:1 to 1:10 ratio.
Abstract: A BASE SHEET MATERIAL ONE SURFACE OF WHICH CARRIES AN OUTER ADHESIVE LAYER, THE OTHER SURFACE OF SAID SHEET MATERIAL CARRYING AN OUTER LAYER OF AN AQUEOUS CONTROLLED RELEASE COATING COMPOSITION COMPRISING A CURED MIXTURE OF AN AQUEOUS ARGANOPOLYSILOXANE EMULSION AND A WATER SOLUBLE HOMOPOLYMER OF COPOLYMER OF AN ALIPHATIC UNSATURATED DIBASIC ACID OR DERIVATIVE THEREOF. AS THE AMOUNT OF SAID WATER SOLUBLE POLYMER INCREASES, THE REQUIRED RELEASE FORCE DECREASES BELOW THAT OF PURE ORGANOPOLYSILOXANE TO A MINIMUM, AND THEN GRADUALLY INCREASES TO A LEVEL ABOVE THAT OF THE ORGANOPOLYSILOXANE. TYPICAL COMPOSITIONS COMPRISE AN AQUEOUS EMULSION OF A POLYMETHYLSILOXANE AND A POLUVINYL METHYL ETHER/MALEIC ANHDRIDE COPOLYMER IN A 10:1 TO 1:10 RATIO ON A WEIGHT BASIS.

7 citations