Showing papers on "Diacylglycerol kinase published in 1961"
TL;DR: If the phosphatidic acid-cycle is a general mechanism for active sodium transport one would expect to find the enzymes of this cycle in all membranes which actively pump sodium, then the presence of these enzymes in erythrocyte membranes is expected.
Abstract: WE have recently provided evidence that in the avian salt gland sodium is pumped by a mechanism which we have termed the phosphatidic acid-cycle1,2. In this mechanism phosphatidate functions as a sodium ion carrier in the membrane; the phosphatidic acid-cycle consists of two enzymes—diglyceride kinase, which forms phosphatidate from diglyceride and adenosine triphosphate, and phosphatidic acid phosphatase, which hydrolyses phosphatidate to yield diglyceride and orthophosphate. If the phosphatidic acid-cycle is a general mechanism for active sodium transport one would expect to find the enzymes of this cycle in all membranes which actively pump sodium. This preliminary report is concerned with the presence of these enzymes in erythrocyte membranes.
51 citations