Showing papers on "Elevated plus maze published in 1985"
TL;DR: A novel test for the selective identification of anxiolytic and anxiogenic drug effects in the rat is described, using an elevated + -maze consisting of two open arms and two enclosed arms, which showed that behaviour on the maze was not clearly correlated either with exploratory head-dipping or spontaneous locomotor activity.
5,391 citations
TL;DR: The behavioural, physiological and pharmacological validation of one animal test of anxiety, the social interaction test, is described in detail and is able to distinguish anxiolytic from sedative effects and is not sensitive to the actions of antidepressants or neuroleptics.
Abstract: The behavioural, physiological and pharmacological validation of one animal test of anxiety, the social interaction test, is described in detail. The effects of anxiolytic and anxiogenic drugs, and manipulations of catecholaminergic and serotonergic pathways are considered. The test is able to distinguish anxiolytic from sedative effects and is not sensitive to the actions of antidepressants or neuroleptics.
149 citations