Showing papers on "Ferrier carbocyclization published in 1993"
TL;DR: Some seco analogues of Amaryllidaceae alkaloids have been prepared in enantiomerically pure form from D-glucose using Ferrier carbocyclization as the key step.
37 citations
TL;DR: Some seco analogues of Amaryllidaceae alkaloids have been prepared in enantiomerically pure form from D-glucose using Ferrier carbocyclization as the key step as mentioned in this paper.
Abstract: Some “seco” analogues of Amaryllidaceae alkaloids narciclasine and lycoricidine have been prepared in enantiomerically pure form from D-glucose using Ferrier carbocyclization as the key step. N-acylation of the resulting amines 21, 22, 25 and 26 with several aromatic acids led to amides 31–34 structurally related to narciclasine and lycoricidine. These seco analogues are devoided of biological activity.
1 citations