Showing papers on "Hand eczema published in 1989"

Epidemiology of different types of hand eczema in an industrial city.

Abstract: Different types of hand eczema in an industrial city were studied. Questionnaires were sent to 20,000 individuals aged 20-65 years, randomly selected from the population register of the city. Those subjects (1,385) considering themselves to have had hand eczema within the previous 12 months were invited to a dermatological examination. It was found that hand eczema occurred twice as often among females as among males. The most common diagnosis was irritant dermatitis. Atopic hand eczema and allergic contact dermatitis had a lower but approximately equal prevalence. Onset of hand eczema at young ages was common, in particular among women. Hand eczema was shown often to be a long-lasting disease with a relapsing course. Atopic hand eczema seemed to be most unfavourable, with a long duration, high continuity of symptoms and extensive involvement.

An epidemiological comparison between occupational and non-occupational hand eczema.

Abstract: Thirty-four per cent of 2110 patients with eczema attending a contact dermatitis clinic had hand eczema. Fifty-five per cent (395 of 721) had contact dermatitis and 45% (326 of 721) had endogenous/unclassifiable eczema. Thirty-five per cent of cases (217 of 721) were occupational eczema. An epidemiological comparison of patients with occupational and non-occupational hand eczema (defined as eczema occurring on the hands up to the wrist line) was made. Hand eczema was more common in males in both groups, and there was a significantly larger proportion of males in the occupational group (65%) than the non-occupational group (51%) (P less than 0.001). The prevalence of a personal or family history of atopy was significantly lower in the occupational group (7%) than the non-occupational group (15%) (P less than 0.005). Irritant contact dermatitis occurred in a larger proportion of patients in the occupational group (76%) than the non-occupational group (39%) (P less than 0.0001). There was no significant difference between the proportions of patients with positive patch test reactions in the occupational group (34%) and the non-occupational group (41%). Potassium dichromate, and epoxy resin allergy occurred significantly, more frequently, in the occupational group whereas fragrance-mix allergy was significantly more frequent in the non-occupational group.

Occupational dermatoses at a film laboratory. Follow-up after modernization.

Abstract: The occurrence and causes of occupational dermatoses at a film laboratory following modernization was studied. In 1983 the film laboratory moved to new premises built to reduce exposure to hazardous chemicals. The study was carried out during 1983-1986 with repeated interviews and dermatological examinations of all employees (78 subjects) and patch testing those with a history of or with current chemical exposure or dermatitis (65 subjects). Of 54 chemically exposed subjects, 34 (63%) had a history of occupational dermatoses, and 12 (22%) were contact allergic to film chemicals. Current, probable occupational dermatoses were observed in 13 subjects--thereof 8 with hand eczema. No new case of occupational skin disease occurred during the investigation period, except for 1 case of ulceration from an acid splash. Petrolatum mixtures of the colour developing agents, Metol and hydroquinone were found most suitable for patch testing, since these chemicals are unstable and/or cause irritation in aqueous solutions. It is concluded that occurrence and severity of occupational dermatoses had been reduced by the technical measures taken to reduce chemical exposure.

Hand eczema associated with continuous subcutaneous insulin infusion.

Abstract: Few similar cases to that presented here have been reported (9-12). Skin tests with different brands of heparin and purified heparin without preservatives show that our patient has a delayed-type hypersensitivity to heparin. Since all brands use highly purified beef or porcine heparin, an allergic reaction to animal protein impurities is unlikely. Low molecular weight heparins are produced by fractionation or depolymerization of standard heparin. Especially with the fractionation method, allergens may persist. This may explain the allergic reaction to low molecular weight heparin in our patient. However, a case of heparin hypersensitivy without allergy to a semi-synthetic low molecular weight heparin has been reported (9). Heparin is a mucopolysaccharide derived from porcine intestinal mucosa or bovine lung. Since heparinoid Org. 10172 is a mucopolysaccharide derived from porcine intestinal mucosa, it may share identical allergens with heparin, thus explaining the allergic reaction to heparinoid in our patient. However, in a case of heparin-induced thrombocytopenia associated with heparin-dependent IgG antibodies, the patient was able to be treated with heparinoid, and IgG antibodies were not directed against it (13). In cases of heparin hypersensitivity, heparinoid or low molecular weight heparin may be usable, but in some cases, additional allergic reactions to heparinoid or low molecular weight heparin may occur. The patient and all controls noticed a burning feeling immediately after the intradermal injection of heparin. Therefore, it is likely that immediatetype skin reactions after intradermal skin tests were the result of irritation by the drug. 8 patients who developed erythematous skin reactions after at least 1 week of therapy with subcutaneous heparin showed only this immediate-type reaction to our skin tests. An allergic reaction to heparin or its preservative in these patients is therefore unlikely (1). The pathogenesis of these lesions is unknown. SHORT COMMUNICATIONS

Systemic Drugs and Palmar Eczema

Abstract: A statistical study of the relationship between vesicular palmar eczema and various clinical variables was carried out. Vesicular palmar eczema was found in 153 patients (38%), whom 113 (74%) were women. Of all the cases found, 92% could be regarded as pompholyx. Three new pathogenetic factors were suggested in vesicular palmar eczema: use of acetylsalicylic acid (Aspirin), contraceptives and smoking. Furthermore, the relationship between pompholyx and contact allergy to nickel was confirmed. No correlation to atopy was found; however, both atopy and sex were found to constitute certain risk groups. The study was based on information from 425 consecutively patch-tested patients (74% women) from our local database DA-LUK.

Contact Dermatitis with Multiple Sensitization in an 8-Year-Old Child

Abstract: We present a case of multiple sensitization in an 8-year-old child who had a serious hand eczema.

Hand eczema in women and, its relationship with atopic diathesis and delivery.

Abstract: 鹿島労災病院皮膚科における主婦手湿疹の患者65症例につきアトピー素因の有無と出産との関係を検討した。全症例の内54例(83%)がアトピー素因を持ち, さらにその内の37例(68%)が出産を機に発症していた。この結果からも主婦手湿疹がアトピー素因と高い相関性を持ち, また出産が手湿疹の発症になんらかの関与をしているものと考えられた。