Showing papers on "Primary systemic amyloidosis published in 1981"
TL;DR: Ophthalmoplegia associated with biopsy-proven amyloid infiltration of the extraocular muscles developed in a 60-year-old man with multiple myeloma may indicate an underlying myel cancer rather than primary systemic amyloidsosis.
22 citations
Journal Article•
TL;DR: The cases of amyloidosis found at autopsy at the Institute of Pathology, Zurich, over the last seven years are reviewed and it is suggested that the ulcer is a consequence of the primary disease.
Abstract: Even severe generalized amyloidoses are difficult to diagnose clinically. By way of example the case is reported of a 64-year-old patient hospitalized for severe abdominal pain who died within a few weeks of heart and circulatory failure. The unusual disease picture is dominated by three cardinal symptoms: large, hemorrhagic-bullous lesions of the skin, recurrent ventricular ulcers with perforation and local peritonitis, and progressive heart failure refractory to therapy. Pathologico-anatomically, amyloid deposits were found in all three organs and primary systemic amyloidosis was diagnosed. Stenotic deposits in the blood vessels and extensive involvement of the ventricular wall suggest that the ulcer is a consequence of the primary disease. The cases of amyloidosis found at autopsy at the Institute of Pathology, Zurich, over the last seven years are reviewed.
6 citations
TL;DR: After 10 days' treatment the facial paraesthesia had ceased and sensation was normal in the right arm and the sensory level on the trunk had descended to T6 on the right and T8 on the left, and he was able to walk with a single stick.
Abstract: treatment the facial paraesthesia had ceased. After a further two days sensation was normal in the right arm and the sensory level on the trunk had descended to T6 on the right and T8 on the left. Grip in the right hand had improved (grade 3-4) and he was again able to move his right leg at the hip and knee (grade 3) and ankle (grade 2). After 10 days' treatment he was able to walk with a single stick. Five weeks after the start of the treatment he was able to walk unaided, having only slight proximal weakness in the right leg. Power was normal in his right hand, though dexterity was impaired. Sensation was normal, with the exception of vibration sensation, which was impaired below the sternum. The plantar response was extensor on the right, and reflexes were brisk in the right leg.
2 citations