Showing papers on "Tartrate-resistant acid phosphatase published in 1974"

Acid phosphatase in developing teeth and bone of man and Macaque monkey.

Abstract: — The activity of acid phosphatase in jaws and teeth from human fetuses and young monkeys has been studied by means of histochemistry. The enzyme was found in all cells of the hard tissues. The highest activities were found in osteoclasts and presecretory ameloblasts. In the monkeys, where the development of the teeth had reached the stage of enamel maturation, an equally high activity was also found in postsecretory ameloblasts. Studies with specific inhibitors suggested that there may be at least three different acid phosphatases present in the cells associated with hard tissue formation and resorption: (1) fluoride and copper resistant, molybdate and tartrate sensitive acid phosphatase was found in secretory and postsecretory ameloblasts, (2) fluoride, copper and molybdate sensitive, tartrate resistant acid phosphatase was found in osteoclasts. and (3) acid phosphatase rather resistant to all the applied inhibitors was found in outer enamel epithelium, stellate reticulum, stratum intermedium, odontoblasts and osteoblasts. The acid phosphatase activity in the enamel organ prior to enamel matrix formation was inhibited similarly to the activity in the oral epithelium and may represent a fourth type.