Showing papers on "Termitomyces clypeatus published in 2018"
TL;DR: The results provided basic information demonstrating the antibacterial activity and immunostimulatory activity of T. clypeatus on both cell-mediated and humoral immunity.
Abstract: Termitomyces clypeatus (T. clypeatus) is an edible mushroom specie which grows in various areas in Cameroon. It is indicated by several healers in treatment of several infectionsand is frequently used for this purpose. However, no study has been reported on its antibacterial and immunomodulatory activities which were the aim of this study. Disc diffusion method was used to appreciate the bactericidal activity against 4 bacteria and 2 yeast species. The immunomodulatory activities were assessed in mice, where the extract was administered by gavage and as supplement in the feed. The treatment was done for 10 days. Delayed type hypersensitivity test was carried out to assess the cell mediated immune response while the effect on humoral immunity was evaluated using hemagglutination assay and mice lethality test.. The body weight was also recorded in mice used for delayed hypersensitivity. It was found that extract of T. clypeatus highly inhibited the growth of bacteria and yeast at different ratios compared to the medium (P < 0.05). The extract of T. clypeatus has reversed the immunosuppressed effects of dexamethasone on antibody formation. In addition, it significantly decreased of the mice lethality rate in mice infected by Pasteurella multocida (P < 0.05). Administration of T. clypeatus also significantly increased the delayed type hypersensitivity response in healthy and dexamethasone immunosuppressed mice (P < 0.05), but it significantly reduced the body weight of mice after 10 days. The results provided basic information demonstrating the antibacterial activity and immunostimulatory activity of T. clypeatus on both cell-mediated and humoral immunity.
11 citations
05 Sep 2018
TL;DR: All the mushroom species are very safe for consumption while the presence of alkaloids, saponins, phenols and flavonoids indicate medicinal potentials, which suggests screening and characterization of the secondary metabolites are required.
Abstract: The present study was carried out to determine the phytochemical and anti nutritional composition of some selected edible mushrooms collected in Ekiti State, Nigeria such as Pleurotus sajor-caju, Termitomyces robustus, Lentinus squarosullus, Termitomyces microcarpous, Termitomyces clypeatus, Lentinus tuber-regium and Polyporus sp. The results of phytochemical analyses revealed the presence of phytochemicals such as alkaloids (0.03-0.17%), saponin (0.03-0.12%), total phenols (0.12-4.32%), flavonoids (0.20-6.04%) and tannins (0.04-2.60%). The least concentration of all the phytochemicals was found in Polyporus sp. Results of anti nutrient screening revealed the presence of phytate (0.17-0.34mg/g), oxalate (1.87-4.04mg/g) and cyanide (0.05-0.27mg/g). Furthermore, results revealed significant differences in the phytochemical as well as anti nutritional composition of the mushrooms though some species had similar compositions. The obtained values of phytochemicals and anti nutrients were significantly lower in all the mushroom species compared to their toxic levels according to World Health Organization stipulated safe limits. Thus, the study suggests that all the mushroom species are very safe for consumption while the presence of alkaloids, saponins, phenols and flavonoids indicate medicinal potentials. Hence, screening and characterization of the secondary metabolites are required.
1 citations