Showing papers on "Totipotent published in 1973"
TL;DR: There is evidence that the development of pre-patterns in vertebrate embryos involves not the counting of the cells but the erection of a “map” of information whereby zones of space are devoted to development of particular differentiations by cells within them.
Abstract: THERE is evidence that the development of pre-patterns in vertebrate embryos involves not the counting of the cells but the erection of a “map” of information whereby zones of space are devoted to development of particular differentiations by cells within them. Thus in amphibian neurulae following initial removal of much of the totipotent blastula, abnormally few cells create a whole pattern, although each cell has normal dimensions. Conversely, in normal-sized Xenopus embryos having haploid cells, an appropriately larger-than-normal number of these smaller cells is assigned to each somite, the somite blocks being normal in number and dimensions1.
57 citations