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Showing papers on "Totipotent published in 1979"


Journal ArticleDOI
TL;DR: In this paper, the authors have produced cell hybrids between totipotent mouse teratocarcinoma cells and rat hepatoma cells, which were tested for the expression of liver specific functions expressed in the hepatoma cell parent and their ability to differentiate when injected into nude mice.
Abstract: We have produced somatic cell hybrids between totipotent mouse teratocarcinoma cells and rat hepatoma cells. These hybrids were tested for the expression of liver specific functions expressed in the hepatoma cell parent and for their ability to differentiate when injected into nude mice. The results of this study indicate that hybrid cell clones do not resemble either of the parental cells, since they do not produce albumin and tyrosine aminotransferase that are expressed in the rat hepatoma parent, and are incapable of forming either teratocarcinomas or hepatomas when injected in experimental animals.

17 citations


Journal Article
TL;DR: The problem of whether the development of leafy shoots is sensitive to near-zero g conditions is considered and a test system that would allow this problem to be resolved in a future space flight is described.
Abstract: Reference is made to the Cosmos 782 experiment, which showed that cultured totipotent cells of carrot can give rise to embryos with well-developed roots but minimally developed shoots at near-zero g. The problem of whether the development of leafy shoots is sensitive to near-zero g conditions is considered. A test system that would allow this problem to be resolved in a future space flight is described.

1 citations