A
A. Alvarez
Researcher at University of Chile
Publications - 6
Citations - 87
A. Alvarez is an academic researcher from University of Chile. The author has contributed to research in topics: Apyrase & ATPase. The author has an hindex of 5, co-authored 6 publications receiving 87 citations.
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Journal ArticleDOI
Human placental ATP-diphosphohydrolase : biochemical characterization, regulation and function
A.M. Kettlun,A. Alvarez,R. Quintar,M.A. Valenzuela,L. Collados,E. Aranda,A. Banda,L. Chayet,Mario Chiong,Marta Mancilla,Aída Traverso-Cori +10 more
TL;DR: Kinetic and physico-chemical studies on human placental microsomal fraction confirmed that the ATPase and ADPase activities detected in this fraction correspond to the enzyme ATP-diphosphohydrolase or apyrase, which is supported by the direct effect on washed platelets and by its plasma membrane localization.
Journal Article
Comparison of the biochemical properties, regulation and function of ATP-diphosphohydrolase from human placenta and rat kidney.
M.A. Valenzuela,A.M. Kettlun,S. Sandoval,Lorena García,Marta Mancilla,G. Neckelmann,L. Chayet,A. Alvarez,F. Cuevas,L. Collados,V. Espinosa,Aída Traverso-Cori,I. Bravo,C. G. Acevedo,E. Aranda +14 more
TL;DR: A comparison of the biochemical properties of human placenta and rat kidney apyrase is presented, showing similarities in Mr. bivalent metal stimulation, nucleotide nonspecificity, insensitivity towards specific ATPase inhibitors, and lack of essential sulfhydryl and aliphatic hydroxyl groups.
El poblat lacustre neolític de la Draga. Excavacions de 1990 a 1998
Àngel Bosch,Júlia Chinchilla,X. Nieto,X. Raurich,Josep Tarrús,Antoni Palomo,A. Alvarez,Francesc Burjachs,D. Brusi,Ramon Buxó,X. Clop,Juan C. Felix,Ll Garcia,P. Gassmann,F. Gibaja,J. Girbal,B. Hug,J. Juan,N. Juan-Muns,J.M. Masip,P. Pauc,Raquel Piqué,A. Planas,J. Reche,J. Reinhard,Núria Rovira,J.M. Rueda,Maria Saña,C. Saüch +28 more
Journal ArticleDOI
ATP-diphosphohydrolase activity in rat renal microvillar membranes and vascular tissue.
S. Sandoval,Lorena García,Marta Mancilla,A.M. Kettlun,L. Collados,L. Chayet,A. Alvarez,Aída Traverso-Cori,M.A. Valenzuela +8 more
TL;DR: The identification of ATP-diphosphohydrolase as an ecto-enzyme both in microvilli and vasculature support the proposal that the enzyme may have an important role in the extracellular metabolism of nucleotides.
Journal ArticleDOI
Changes in apyrase activity in uterus and mammary gland during the lactogenic cycle.
M.A. Valenzuela,L. Collados,A.M. Kettlun,Marta Mancilla,Javier Puente,E. Aranda,L. Chayet,A. Alvarez,Aída Traverso-Cori +8 more
TL;DR: A significant decrease in apyrase activity (ATPase-ADPase) was observed in the pregnant uterus; this observation correlates with a minor inhibitory effect on platelet aggregation.