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A.C. Van Steirteghem

Researcher at VU University Amsterdam

Publications -  41
Citations -  2414

A.C. Van Steirteghem is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Embryo transfer & Pregnancy rate. The author has an hindex of 23, co-authored 41 publications receiving 2382 citations.

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Conventional in vitro fertilization versus intracytoplasmic sperm injection for patients requiring microsurgical sperm aspiration

TL;DR: ICSI (using epididymal or testicular spermatozoa) from men with CBAVD or irreparable obstructive azoospermia, achieved good fertilization and normal embryos in 82% of cases, compared to 19% with conventional IVF.
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The luteal phase and early pregnancy after combined GnRH-agonist/HMG treatment for superovulation in IVF or GIFT

TL;DR: Endometrial biopsies showing inadequate development were observed after ovarian stimulation with the GnRH agonist Buserelin and HMG for IVF or GIFT when luteal supplementation was omitted, and temporarily defective function of the corpus luteum was evidenced by measuring serum progesterone, 17 beta-oestradiol and 17-hydroxyprogesterone.
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Management of failed cycles in an IVF/GIFT programme with the combination of a GnRH analogue and HMG.

TL;DR: The addition of the gonadotropin releasing hormone (GnRH) agonist Buserelin to human menopausal gonadotrophin/human chorionic gonadotropic hormone (HMG/HCG) during ovarian stimulation was evaluated in 23 cycles of 21 women who previously had unsuccessful IVF treatments when stimulated with clomiphene--HMG-HCG.
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Avoidance of triplet pregnancies by elective transfer of two good quality embryos

TL;DR: Limiting the number of transferred embryos to two where the prognosis is otherwise good has now become standard practice in this centre, and a significant lowering of pregnancy rate was found.
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Chorionic gonadotrophin-β mRNA, a trophoblast marker, is expressed in human 8-cell embryos derived from tripronucleate zygotes

TL;DR: This work sees expression of HCG-beta RNA at the 6-8-cell stage, before morphological differentiation between trophectoderm and inner cell mass is apparent and believes that this RNA is the product of de novo transcription from the embryonic genome, since transcripts are only observed in embryos of at least 2 days post-fertilization in age.