A. Cassaigne

TL;DR: Alcoholics who are GSTμ(–) and ADH31/ADH31 have at least an 80% greater risk of developing laryngeal cancer than alcoholic individuals who have GSTμ [GSTμ(+)] and are not ADH 31/ADh31.

TL;DR: A genotyping procedure is proposed for apo E that characterizes a given allele on the basis of amplification of specific sequences of the gene followed by the action of restriction endonucleases.

TL;DR: Plasma interleukin-6 and especially tumour necrosis factor alpha determined on the day of the rejection diagnosis were significantly increased in the patient sample with moderate or severe rejection when compared with mean values of interlekines and tumour Necrosis factoralpha in the customer sample without rejection or with mild rejection.

TL;DR: Comparison of alcohol dehydrogenase polymorphism at the loci ADH2 and ADH3 is made in France between 46 alcoholic cirrhotic patients and 39 controls by genotyping technique using polymerase chain reaction on blood microsample collected on blotting paper.

TL;DR: A procedure for ALDH I2 detection consisting in a differentiation between the 'atypical' allele and the 'wild' allele has been improved through PCR and subsequent MboII digestion, which permits a rapid and non-radioactive detection of atypical AL DH I2 on a PCR product without the use of allele specific oligonucleotides.