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A. Díaz
Researcher at University of Antioquia
Publications - 25
Citations - 1000
A. Díaz is an academic researcher from University of Antioquia. The author has contributed to research in topics: Antivenom & Scorpion stings. The author has an hindex of 13, co-authored 25 publications receiving 929 citations.
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Journal ArticleDOI
Complications of Bothrops, Porthidium, and Bothriechis snakebites in Colombia. A clinical and epidemiological study of 39 cases attended in a university hospital
Rafael Otero,Johnayro Gutiérrez,Marı́a Beatriz Mesa,Edison Duque,Orlando Rodrı́guez,Jorge Luis Arango,Francisco Gómez,Álvaro Wills Toro,Fidel Cano,Libia M. Rodríguez,Erika Caro,J. Martínez,William Cornejo,Luis Mariano Gómez,Francisco Luis Uribe,Silvia Cárdenas,Vitelbina Núñez,A. Díaz +17 more
TL;DR: The clinical and epidemiological features, as well as complications presented by 39 patients with Bothrops, Porthidium and Bothriechis snakebites, are described.
Journal ArticleDOI
A randomized blinded clinical trial of two antivenoms, prepared by caprylic acid or ammonium sulphate fractionation of IgG, in Bothrops and Porthidium snake bites in Colombia: correlation between safety and biochemical characteristics of antivenoms.
Rafael Otero,José María Gutiérrez,Gustavo Rojas,V Núñez,A. Díaz,E Miranda,A.F Uribe,Juan F. Silva,J.G Ospina,Y. Medina,María Fabiola Toro,M.E. Garcı́a,Guillermo León,M. E. Garcia,Sergio Lizano,J De La Torre,Juan Gómez Márquez,Y. Mena,Niurca González,L.C Arenas,A Puzón,N Blanco,A. Sierra,M.E Espinal,M Arboleda,J.C Jiménez,Patricia Ramírez,Manuel Cánovas Díaz,M.C Guzmán,J Barros,S Henao,Amelie G. Ramirez,U Macea,R Lozano +33 more
TL;DR: A randomized blinded clinical trial was performed in 53 patients bitten by Bothrops sp.
Journal ArticleDOI
Ontogenetic variability of Bothrops atrox and Bothrops asper snake venoms from Colombia.
Mónica Saldarriaga,Rafael Otero,Vitelbina Núñez,María Fabiola Toro,A. Díaz,José María Gutiérrez +5 more
TL;DR: Venom of adult specimens showed a higher number of peaks with indirect hemolytic activity than venom of newborn specimens, and polyvalent antivenom produced in Costa Rica recognized all the bands of both venoms from specimens at all ages tested, when assayed by Western blotting.
Journal ArticleDOI
Neutralization of the edema-forming, defibrinating and coagulant effects of Bothrops asper venom by extracts of plants used by healers in Colombia.
Vitelbina Núñez,Rafael Otero,Jacqueline Barona,Mónica Saldarriaga,R.G. Osorio,R. Fonnegra,Silvia L. Jiménez,A. Díaz,Juan C Quintana +8 more
TL;DR: The neutralizing activity of 12 ethanolic extracts of plants against the edema-forming, defibrinating and coagulant effects of Bothrops asper venom in Swiss Webster mice was determined.
Journal ArticleDOI
Efficacy and safety of two whole IgG polyvalent antivenoms, refined by caprylic acid fractionation with or without β-propiolactone, in the treatment of Bothrops asper bites in Colombia
Rafael Otero,Guillermo León,José María Gutiérrez,Gustavo Rojas,María Fabiola Toro,Jacqueline Barona,Verónica Rodríguez,A. Díaz,Vitelbina Núñez,Juan C Quintana,Shirley Ayala,Diana Carolina Mosquera,Lesdy L. Conrado,Diego Fernández,Yobana Arroyo,Carlos A. Paniagua,Mercedes López,Carlos E. Ospina,Claudia Patricia Alzate,Jorge Fernández,Jazmín J. Meza,Juan F. Silva,Patricia Ramírez,Patricia E. Fabra,Eugenio Ramírez,Elkin A. Córdoba,Ana Berta Arrieta,David A. Warrell,R. David G. Theakston +28 more
TL;DR: There were no significant differences between the two antivenoms in the time taken to reverse venom-induced bleeding and coagulopathy, to restore physiological fibrinogen concentrations and to clear serum venom antigenaemia.