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A. E. Tinch
Researcher at University of Stirling
Publications - 23
Citations - 1726
A. E. Tinch is an academic researcher from University of Stirling. The author has contributed to research in topics: Population & Quantitative trait locus. The author has an hindex of 17, co-authored 22 publications receiving 1488 citations.
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Journal ArticleDOI
Major quantitative trait loci affect resistance to infectious pancreatic necrosis in Atlantic salmon (Salmo salar).
Ross D. Houston,Chris Haley,Alastair Hamilton,Derrick R Guy,A. E. Tinch,John B. Taggart,Brendan McAndrew,Stephen Bishop +7 more
TL;DR: The identified genomewide quantitative trait loci can be applied in marker-assisted selection programs to improve the resistance of salmon to IPN and reduce disease-related mortality.
Journal ArticleDOI
Development and validation of a high density SNP genotyping array for Atlantic salmon (Salmo salar)
Ross D. Houston,John B. Taggart,Timothe Cezard,Michaël Bekaert,Natalie R Lowe,Alison Downing,Richard Talbot,Stephen Bishop,Alan Archibald,James E. Bron,David J. Penman,Alessandro Davassi,Fiona Brew,A. E. Tinch,Karim Gharbi,Alastair Hamilton +15 more
TL;DR: This manuscript describes the first high-density SNP genotyping array for Atlantic salmon, likely to be used as a platform for high-resolution genetics research into traits of evolutionary and economic importance in salmonids and in aquaculture breeding programs via genomic selection.
Journal ArticleDOI
Genome wide association and genomic prediction for growth traits in juvenile farmed Atlantic salmon using a high density SNP array
Hsin-Yuan Tsai,Alastair Hamilton,A. E. Tinch,Derrick R Guy,Karim Gharbi,Michael J. Stear,Oswald Matika,Steve C. Bishop,Ross D. Houston +8 more
TL;DR: The high density SNP array can effectively capture the additive genetic variation in complex traits, however, the traits of weight and length both appear to be very polygenic with only one SNP surpassing the chromosome-wide threshold.
Journal ArticleDOI
Genomic prediction of host resistance to sea lice in farmed Atlantic salmon populations
Hsin-Yuan Tsai,Alastair Hamilton,A. E. Tinch,Derrick R Guy,James E. Bron,John B. Taggart,Karim Gharbi,Michael J. Stear,Oswald Matika,Ricardo Pong-Wong,Steve C. Bishop,Ross D. Houston +11 more
TL;DR: Host resistance to sea lice in farmed Atlantic salmon has a significant genetic component, and Phenotypes relating to host resistance can be predicted with moderate to high accuracy within populations, with a major advantage of genomic over pedigree-based methods, even at relatively sparse SNP densities.
Journal ArticleDOI
The susceptibility of Atlantic salmon fry to freshwater infectious pancreatic necrosis is largely explained by a major QTL
Ross D. Houston,Chris Haley,Chris Haley,Alister Hamilton,Derrick R Guy,J. C. Mota-Velasco,Almas Gheyas,A. E. Tinch,John B. Taggart,James E. Bron,W. G. Starkey,Brendan McAndrew,David W. Verner-Jeffreys,Richard Paley,Georgina S. E. Rimmer,I. Tew,Stephen Bishop +16 more
TL;DR: The results suggest that a single QTL on linkage group 21 explains almost all the genetic variation in IPN mortality under the authors' experimental conditions, and highlight the importance of the major QTL in the genetic regulation of IPN resistance across distinct physiological lifecycle stages, environmental conditions and viral isolates.