A. Luxen

TL;DR: Seven protocadherin 19 (PCDH19) gene mutations in seven families with EFMR resulted in the introduction of a premature termination codon and two missense mutations were predicted to affect adhesiveness of PCDH19 through impaired calcium binding.

TL;DR: It is proposed that these cortical maps are best explained by the recruitment of visual attention and memory structures, which play a major role in prospective time judgements as indicated by behavioral studies.

TL;DR: In this article, a radiofluorodemercuration of the 6-mercurio derivative 5 with [ 18 F]acetylhypofluorite afforded, after acidic hydrolysis, 6-[ 18 F]-fluoro- l -3,4-dihydroxyphenylalanine (6-FD, 1 ) with a radiochemical yield of 11% (decay corrected and based on the total amount of [18 F]F 2 recovered from the target).

TL;DR: Analysis of cerebral metabolism in these structures indicated a linear accumulation of total radioactivity: a striatum/cerebellum ratio of 2 was observed by 60 min and will serve as the basis for the development of kinetic models of [18F]FDOPA metabolism that can be applied to the evaluation of central dopamine biochemistry with positron emission tomography in humans.

TL;DR: A computer-controlled general purpose chemistry process control unit (CPCU) suitable for the automated production of radiochemicals has been developed and configured and programmed to synthesize 2-deoxy-2-[18F]fluoro-D-glucose (2-[ 18F]FDG) using aqueous [18F]-fluoride ion.