A
A M Rowland
Researcher at Genentech
Publications - 2
Citations - 1403
A M Rowland is an academic researcher from Genentech. The author has contributed to research in topics: Vascular endothelial growth factor A & Growth factor. The author has an hindex of 2, co-authored 2 publications receiving 1386 citations.
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Journal ArticleDOI
Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms.
TL;DR: The bioavailability of V EGF may be regulated at the genetic level by alternative splicing that determines whether VEGF will be soluble or incorporated into a biological reservoir and also through proteolysis following plasminogen activation.
Journal ArticleDOI
Expression of vascular endothelial growth factor does not promote transformation but confers a growth advantage in vivo to Chinese hamster ovary cells.
Napoleone Ferrara,Jane Winer,T Burton,A M Rowland,M. W. Siegel,Heidi S. Phillips,T Terrell,Gilbert-Andre Keller,A D Levinson +8 more
TL;DR: Findings indicate that the expression of VEGF may confer on cells the ability to grow in vivo in the absence of transformation by purely paracrine mechanisms.