Publisher Summary This chapter discusses separate pools of CNS zinc, which are, vesicular zinc, free zinc, and protein-bound zinc Vesicular zinc is the one which is sequestered in the presynaptic vesicles of a special class of neurons, the zinc-containing neurons, which are found primarily in limbic, cerebrocortical, and corticofugal systems This vesicular zinc can be selectively stained by several histochemical procedures and is, therefore, accessible to histological and histoanalytical studies The second pool, free zinc, is an entirely hypothetical pool of ionic Zn +2 in the cytosol or interstitial fluid that may or may not be present in normal, healthy brain tissue The third pool of zinc is that which is bound firmly into the structure of the many zinc-containing enzymes in the brain The enzymatic zinc is, therefore, a stable pool, involved only in the specific function of the zinc-containing enzymes Zinc metalloenzymes are essential to the normal biology of brain cells, and any experimental treatment that is extreme enough to affect the metalloenzymes, such as prolonged zinc undernutrition or administration of chelators, can disrupt brain function through metalloenzymatic effects

Neurobiology of zinc and zinc-containing neurons.

Oxygen free radicals and metallothionein

A simple spectrophotometric method for metallothionein evaluation in marine organisms: an application to Mediterranean and Antarctic molluscs

Silver, known in metallic form since antiquity, has very early been recognized by mankind for its antimicrobial properties, a phenomenon observed, for example, in the context of drinking water (a silver coin in a well), food (silver cutlery, water storage recipients), and medicine (silver skull plates, teeth). Silver compounds were also shown to be useful. For example, dilute solutions of silver nitrate served long, and still do in some countries, as antimicrobial ointment to be instilled into Published in \" \" which should be cited to refer to this work.

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Nanobio Silver: Its Interactions with Peptides and Bacteria, and Its Uses in Medicine

Molecular and ionic mimicry and the transport of toxic metals.

Quantification of metallothioneins by a silver-saturation method

The influence of manganese on the distribution of essential trace elements: I. Regional distribution of Mn, Na, K, Mg, Zn, Fe, and Cu in rat brain after chronic Mn exposure

A.M. Scheuhammer

Papers

Quantification of metallothioneins by a silver-saturation method

The influence of manganese on the distribution of essential trace elements: I. Regional distribution of Mn, Na, K, Mg, Zn, Fe, and Cu in rat brain after chronic Mn exposure

The distribution and excretion of manganese: the effects of manganese dose, L-dopa, and pretreatment with zinc.