A
A. Mathur
Researcher at Novartis
Publications - 35
Citations - 6016
A. Mathur is an academic researcher from Novartis. The author has contributed to research in topics: Bone mineral & Quantitative computed tomography. The author has an hindex of 22, co-authored 34 publications receiving 5858 citations. Previous affiliations of A. Mathur include University of California, San Francisco.
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Journal ArticleDOI
Effects of an interleukin-5 blocking monoclonal antibody on eosinophils, airway hyper-responsiveness, and the late asthmatic response
Margaret J Leckie,Anneke ten Brinke,Jamey Khan,Zuzana Diamant,Brian J. O'Connor,Christine M Walls,A. Mathur,Hugh C Cowley,K. Fan Chung,Ratko Djukanovic,Trevor T. Hansel,Stephen T. Holgate,Peter J. Sterk,Peter J. Barnes +13 more
TL;DR: A single dose of monoclonal antibody to IL-5 decreased blood eosinophils for up to 16 weeks and sputum eosInophils at 4 weeks, which has considerable therapeutic potential for asthma and allergy, however, the findings question the role of eos inophils in mediating the late asthmatic response and causing airway hyper-responsiveness.
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Noninvasive assessment of bone mineral and structure: state of the art.
Harry K. Genant,Klaus Engelke,Thomas Fuerst,Claus-C. Glüer,Stephan Grampp,Steven T. Harris,M. Jergas,Thomas Lang,Ying Lu,Sharmila Majumdar,A. Mathur,Masa Takada +11 more
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Correlation of trabecular bone structure with age, bone mineral density, and osteoporotic status: in vivo studies in the distal radius using high resolution magnetic resonance imaging.
Sharmila Majumdar,Harry K. Genant,Stephan Grampp,David C. Newitt,V. H. Truong,J. C. Lin,A. Mathur +6 more
TL;DR: High resolution magnetic resonance imaging, a potentially useful tool for quantifying trabecular structure in vivo, may have applications for understanding and evaluating skeletal changes related to age and osteoporosis.
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Comparisons of noninvasive bone mineral measurements in assessing age-related loss, fracture discrimination, and diagnostic classification.
Stephan Grampp,Harry K. Genant,A. Mathur,Philipp Lang,M. Jergas,M. Takada,Claus-C. Glüer,Ying Lu,Monica Chavez +8 more
TL;DR: This study examined the commonly available methods of noninvasively assessing bone mineral status across three defined female populations to examine their interrelationships, compare their respective abilities to reflect age‐ and menopause‐related bone loss, discriminate osteoporotic fractures, and classify patients diagnostically.
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Volumetric quantitative computed tomography of the proximal femur: Precision and relation to bone strength
TL;DR: Trabecular BMD measurements were reproducible and highly correlated to biomechanical strength measurements, and support further exploration of quantitative CT for assessment of osteoporosis at the proximal femur.