A
A. Simionovici
Researcher at European Synchrotron Radiation Facility
Publications - 42
Citations - 477
A. Simionovici is an academic researcher from European Synchrotron Radiation Facility. The author has contributed to research in topics: Cosmic dust & Microprobe. The author has an hindex of 13, co-authored 42 publications receiving 470 citations. Previous affiliations of A. Simionovici include École normale supérieure de Lyon.
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Journal ArticleDOI
Microimaging and tomography with chemical speciation
TL;DR: In this article, the results of X-ray absorption near-edge spectroscopy (XANES) imaging and tomography obtained measuring a phantom sample of pure molybdenum compounds using a FreLoN 2000 camera system at the ESRF undulator beamline ID22.
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Lack of Cell Death Enhancement after Irradiation with Monochromatic Synchrotron X Rays at the K-Shell Edge of Platinum Incorporated in Living SQ20B Human Cells as cis-Diamminedichloroplatinum (II)
Stéphanie Corde,Marie-Claude Biston,H. Elleaume,François Estève,A. M. Charvet,Aurélie Joubert,V. Ducros,Sylvain Bohic,A. Simionovici,Thierry Brochard,Christian Nemoz,Michel Renier,Irène Troprès,Stefan Fiedler,Alberto Bravin,William Thomlinson,J.F. Le Bas,Jacques Balosso +17 more
TL;DR: This was the first known attempt at K-shell edge photon activation of stable platinum in living cells with a platinum complex used for chemotherapy, and it is proposed that cisplatin toxicity can mask the enhancement of cell death induced by the irradiation above the K- shell edge.
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Topographic and quantitative microanalysis of human central nervous system tissue using synchrotron radiation
Magdalena Szczerbowska-Boruchowska,Marek Lankosz,J. Ostachowicz,Dariusz Adamek,Anna Krygowska-Wajs,Barbara Tomik,Andrzej Szczudlik,A. Simionovici,Sylvain Bohic +8 more
TL;DR: The present investigation showed that the μ-SXRF technique is suitable for elemental analysis at the single cell level in applications in neurological research.
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Implementation of X-ray Fluorescence Microscopy for Investigation of Elemental Abnormalities in Amyotrophic Lateral Sclerosis
Barbara Tomik,Joanna Chwiej,Magdalena Szczerbowska-Boruchowska,Marek Lankosz,S. Wojcik,Dariusz Adamek,G. Falkenberg,Sylvain Bohic,A. Simionovici,Zdzislaw Stegowski,Andrzej Szczudlik +10 more
TL;DR: Investigation of the elemental composition of the gray matter, nerve cells and white matter from spinal cord tissues representing three ALS cases and five non-ALS controls showed no general abnormalities in the elemental accumulation between the ALS and the control group, but for individual ALS cases such abnormalities were observed for the nerve cells.
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X-ray microtome by fluorescence tomography
A. Simionovici,Marina Chukalina,F. Günzler,Ch. Schroer,A. A. Snigirev,Irina Snigireva,J. Tümmler,Timm Weitkamp +7 more
TL;DR: The X-ray fluorescence microtomography method is presented in this paper, which is capable of virtually slicing samples to obtain cross-sections of their inner structure, and high precision experimental results of fluo-tomography in "pencil-beam" geometry with up to 1.2μm resolution are described.