A. Van Der Gen

TL;DR: Results clearly indicate that glutathione conjugation plays an important role in the mutagenicity of 1,2-dibromoethane, where after an initial rise in the number of mutants with increasing amounts of glutATHione, theNumber of mutations decreases again.

TL;DR: Chiral acyloins of high optical purity have been obtained in good yields by enzyme catalyzed formation of optically active cyanohydrins, followed by hydroxyl protection and reaction with a Grignard reagent as discussed by the authors.

TL;DR: The GSH-binding site of glutathione S-transferase (GST) isoenzymes was studied by investigating their substrate-specificity for three series of GSH analogues; further, a model of the interactions of G SH with the G-site is proposed and appears to be very critical with respect to a correct orientation of the thiol group of the GSH analogue.

TL;DR: Asymmetric hydrocyanation of aldehydes was accomplished using almond meal, containing the enzyme oxynitrilase as discussed by the authors, which achieved high levels of enantiomeric purity.

TL;DR: In this article, Silylated cyanohydrins of benzaldehyde, 4-methoxybenzaldehyde, piperonal, 5-methylfurfural, butyraldehyde and crotonaldehyde were obtained in good yield and high enantiomeric excess (93%) after treatment with silyl chlorides and imidazole in DMF.