A
Abril Carbajal-García
Researcher at National Autonomous University of Mexico
Publications - 7
Citations - 97
Abril Carbajal-García is an academic researcher from National Autonomous University of Mexico. The author has contributed to research in topics: Adrenergic & Myocyte. The author has an hindex of 4, co-authored 5 publications receiving 48 citations.
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Book ChapterDOI
Sex Hormones and Lung Inflammation.
TL;DR: In this paper, the most recent advances in the functional roles and associated signaling pathways of inflammatory cellular responses in asthma, COPD, pulmonary fibrosis (PF), lung cancer (LC), and newly occurring COVID-19 disease are summarized.
Journal ArticleDOI
Testosterone induces hyporesponsiveness by interfering with IP3 receptors in guinea pig airway smooth muscle.
Luis M. Montaño,Edgar Flores-Soto,Jorge Reyes-García,Verónica Díaz-Hernández,Abril Carbajal-García,Elías Campuzano-González,G. Lizbeth Ramírez-Salinas,Marco A. Velasco-Velázquez,Bettina Sommer +8 more
TL;DR: It is concluded that TES modifies ITPR1 function in airway smooth muscle, turning this tissue less reactive to contractile agonists that act through PLCβ-IP3 signaling cascade, which might be related to the low asthma prevalence in males from puberty to adulthood.
Journal ArticleDOI
Sex steroids effects on guinea pig airway smooth muscle tone and intracellular Ca 2+ basal levels
Edgar Flores-Soto,Jorge Reyes-García,Abril Carbajal-García,Elías Campuzano-González,Mercedes Perusquía,Bettina Sommer,Luis M. Montaño +6 more
TL;DR: DHEA and TES diminish ASM tone and b[Ca2+]i by blocking L-VDCC and probably a constitutively active TRPC3, and by PGE2 synthesis.
Journal ArticleDOI
Androgen Effects on the Adrenergic System of the Vascular, Airway, and Cardiac Myocytes and Their Relevance in Pathological Processes.
TL;DR: Androgens play an essential role in the adrenergic system of vascular, airway, and cardiac myocytes, favoring either a state of health or disease, and the vascular system is warmly affected.
Journal ArticleDOI
Testosterone augments β2 adrenergic receptor genomic transcription increasing salbutamol relaxation in airway smooth muscle
Abril Carbajal-García,Jorge Reyes-García,María F. Casas-Hernández,Edgar Flores-Soto,Verónica Díaz-Hernández,Héctor Solís-Chagoyán,Bettina Sommer,Luis M. Montaño +7 more
TL;DR: Chronic exposure to physiological TES concentration of the guinea pig ASM promotes β2-AR upregulation favoring β2 adrenergic responses and probably limiting the severity of the asthmatic exacerbations in teenage boys and men.