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Adeline Barthet-Barateig
Researcher at University of Nottingham
Publications - 3
Citations - 212
Adeline Barthet-Barateig is an academic researcher from University of Nottingham. The author has contributed to research in topics: Polyadenylation & Cordycepin. The author has an hindex of 2, co-authored 3 publications receiving 189 citations.
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Journal ArticleDOI
Cordycepin inhibits protein synthesis and cell adhesion through effects on signal transduction.
Ying Ying Wong,Alice Moon,Ruth Duffin,Adeline Barthet-Barateig,Hedda A. Meijer,Michael J. Clemens,Cornelia H. de Moor +6 more
TL;DR: It is confirmed that cordycepin reduces the length of poly(A) tails, with some mRNAs being much more sensitive than others, and it is concluded that many of the reported biological effects of cordyCEpin are likely to be due to its effects on mTOR and AMPK signaling.
Journal ArticleDOI
Inhibition of polyadenylation reduces inflammatory gene induction
Alexander Kondrashov,Hedda A. Meijer,Adeline Barthet-Barateig,Hannah N. Parker,Asma Khurshid,Sarah Tessier,Marie Sicard,Alan J. Knox,Linhua Pang,Cornelia H. de Moor +9 more
TL;DR: It is demonstrated that there are differences in the 3' processing of inflammatory and housekeeping genes and polyadenylation is identified as a novel target for anti-inflammatory drugs.
Posted ContentDOI
Nuclear poly(A) tail size is regulated by Cnot1 during the serum response
Richa Singhania,Graeme J. Thorn,Kathryn S. Williams,Raj D. Gandhi,Clara Daher,Adeline Barthet-Barateig,Hannah N. Parker,Wahyu Utami,Mustafa Al-Siraj,David A. Barrett,Jonathan A. D. Wattis,Cornelia H. de Moor +11 more
TL;DR: The data show that initial poly(A) tail size of mRNAs can be regulated and is not always 200-250 nucleotides, adding a novel layer to the control of gene expression.