Showing papers by "Adrian C Bateman published in 2006"
TL;DR: Higher levels of COX-2 expression are associated with poor clinico-pathologic features and poor survival in patients with oesophageal adenocarcinoma.
Abstract: Background
COX-2 expression in tumour cells has been associated with poor prognosis in gastrointestinal and non-gastrointestinal cancers. The aim of our study was to test the hypothesis that higher levels of COX-2 expression are prognostically related to poor clinico-pathologic features in adenocarcinoma of the oesophagus.
38 citations
TL;DR: A 58-year-old man underwent upper gastrointestinal surveillance endoscopy for Barrett’s oesophagus and showed a possible gastric ulcer, although histological examination was normal.
Abstract: A 58-year-old man underwent upper gastrointestinal surveillance endoscopy for Barrett's oesophagus. This showed a possible gastric ulcer, although histological examination was normal. Follow-up endoscopy showed white ridges in the distal duodenum and these were subjected to biopsy. Histological examination of the biopsy specimens showed polypoid duodenal mucosa showing features similar to those of a hyperplastic polyp of the colon. In addition, the mucosal surface was focally of gastric surface type. The features were interpreted overall as most likely to represent an unusual form of regenerative change in the setting of previous chronic inflammatory mucosal damage. The case is presented as an unusual histological phenomenon at this site; it would be important not to overdiagnose neoplasia in this situation.
14 citations
TL;DR: A wide spectrum of benign changes may occur within breast tissue, including non-neoplastic conditions such as fibrocystic change and benign neoplasms (tumours).
8 citations
TL;DR: The pathologist undertakes these roles as a member of the breast cancer multidisciplinary team (MDT), who meet regularly within each breast cancer unit to discuss new patients who may have breast cancer and those with confirmed diagnoses in which the treatment plan requires definition.
2 citations