A
Adrian C Bateman
Researcher at University Hospital Southampton NHS Foundation Trust
Publications - 146
Citations - 8121
Adrian C Bateman is an academic researcher from University Hospital Southampton NHS Foundation Trust. The author has contributed to research in topics: Cancer & Neoadjuvant therapy. The author has an hindex of 42, co-authored 142 publications receiving 7188 citations. Previous affiliations of Adrian C Bateman include Royal Hampshire County Hospital & National Health Service.
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Journal ArticleDOI
Consensus statement on the pathology of IgG4-related disease
Vikram Deshpande,Yoh Zen,John Kc Chan,Eunhee E Yi,Yasuharu Sato,Tadashi Yoshino,Günter Klöppel,J. Godfrey Heathcote,Arezou Khosroshahi,Judith A. Ferry,Rob C. Aalberse,Daniel Bloch,William R. Brugge,Adrian C Bateman,Mollie N. Carruthers,Suresh T. Chari,Wah Cheuk,Lynn D. Cornell,Carlos Fernandez-del Castillo,David G. Forcione,Daniel L. Hamilos,Terumi Kamisawa,Satomi Kasashima,Shigeyuki Kawa,Mitsuhiro Kawano,Gregory Y. Lauwers,Yasufumi Masaki,Yasuni Nakanuma,Kenji Notohara,Kazuichi Okazaki,Ji Kon Ryu,Takako Saeki,Dushyant V. Sahani,Thomas C. Smyrk,James Robert Stone,Masayuki Takahira,George Webster,Motohisa Yamamoto,Giuseppe Zamboni,Hisanori Umehara,John H. Stone +40 more
TL;DR: This statement proposes a terminology scheme for the diagnosis of IgG4-related disease that is based primarily on the morphological appearance on biopsy, and advocates the use of strict criteria for accepting newly proposed entities or sites as components of the IgG 4- related disease spectrum.
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Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression
Kimberley D. Bruce,Felino R. Cagampang,Marco Argenton,Junlong Zhang,Priya L. Ethirajan,Graham C. Burdge,Adrian C Bateman,Geraldine F. Clough,Lucilla Poston,Mark A. Hanson,Josie McConnell,Christopher D. Byrne +11 more
TL;DR: Maternal fat intake contributes toward the NAFLD progression in adult offspring, which is mediated through impaired hepatic mitochondrial metabolism and up‐regulated hepatic lipogenesis.
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Chemokine expression in IBD. Mucosal chemokine expression is unselectively increased in both ulcerative colitis and Crohn's disease.
TL;DR: It is concluded that human colonic chemokine expression is non‐selectively up‐regulated in IBD and supported the hypothesis that the degree of local inflammation and tissue damage in UC and CD is dependent on local expression of specific chemokines within IBD tissues.
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Type I collagen promotes the malignant phenotype of pancreatic ductal adenocarcinoma.
Thomas Armstrong,Graham Packham,Lindsay B. Murphy,Adrian C Bateman,John A. Conti,David R. Fine,Colin D. Johnson,R. Christopher Benyon,John P. Iredale +8 more
TL;DR: A mechanism by which the desmoplastic reaction in pancreatic cancer may form and, via the collagen within it, promote the malignant phenotype of Pancic cancer cells is elucidated, suggesting significant detriment to the host.
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Expression of Transforming Growth Factor-β1 by Pancreatic Stellate Cells and Its Implications for Matrix Secretion and Turnover in Chronic Pancreatitis
Fanny Shek,Robert Christopher Benyon,Fiona Walker,Peter Raymond McCrudden,Sylvia L.F. Pender,Elizabeth J. Williams,Penelope Ann Johnson,Colin D. Johnson,Adrian C Bateman,David R. Fine,John P. Iredale +10 more
TL;DR: Pancreatic stellate cells express both mediators of matrix remodeling and the regulatory cytokine TGF-beta 1 that, by autocrine inhibition of MMP-3 and M MP-9, may enhance fibrogenesis by reducing collagen degradation.