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Ahuvi Yearim
Researcher at Tel Aviv University
Publications - 4
Citations - 886
Ahuvi Yearim is an academic researcher from Tel Aviv University. The author has contributed to research in topics: Exon & RNA splicing. The author has an hindex of 4, co-authored 4 publications receiving 763 citations. Previous affiliations of Ahuvi Yearim include Hebrew University of Jerusalem.
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The alternative role of DNA methylation in splicing regulation
TL;DR: Two different mechanisms convey DNA methylation information into the regulation of alternative splicing, but only a fraction of such events are regulated, implying that more underlying mechanisms remain to be found.
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DNA-methylation effect on cotranscriptional splicing is dependent on GC architecture of the exon–intron structure
TL;DR: The results suggest that DNA methylation affects exon recognition and is influenced by the GC architecture of the exon and flanking introns.
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HP1 Is Involved in Regulating the Global Impact of DNA Methylation on Alternative Splicing
Ahuvi Yearim,Sahar Gelfman,Sahar Gelfman,Ronna Shayevitch,Shai Melcer,Ohad Glaich,Jan-Philipp Mallm,Malka Nissim-Rafinia,Ayelet-Hashahar Shapira Cohen,Karsten Rippe,Eran Meshorer,Gil Ast +11 more
TL;DR: This work constructed an experimental system using site-specific targeting of a methylated/unmethylated gene and demonstrates a direct causal relationship between DNA methylation and alternative splicing and identifies a specific mechanism of splicing regulation mediated by HP1.
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The tumor suppressor Lgl1 regulates NMII-A cellular distribution and focal adhesion morphology to optimize cell migration
TL;DR: Results indicate that Lgl1 regulates the polarity of migrating cells by controlling NMII-A filament assembly.