A
Akihiko Yonekura
Researcher at Nagasaki University
Publications - 75
Citations - 1082
Akihiko Yonekura is an academic researcher from Nagasaki University. The author has contributed to research in topics: Quantitative computed tomography & Bone mineral. The author has an hindex of 17, co-authored 68 publications receiving 860 citations.
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Localisation of apoptosis and expression of apoptosis related proteins in the synovium of patients with rheumatoid arthritis.
TL;DR: The findings indicate that RA synovial cells undergo apoptosis in addition to cell proliferation, but the frequency of apoptosis was very low, and it is suspected that the apoptotic process in the RAsynovium may be suppressed by over-expression of Bcl-2.
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Antimicrobial susceptibility of Staphylococcus aureus and Staphylococcus epidermidis biofilms isolated from infected total hip arthroplasty cases.
TL;DR: The MBCs of antimicrobial agents for biofilms bacteria were higher than those of planktonic bacteria, and it is suggested that implant-related infection is difficult to treat with antimicrobial agent alone.
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Early Staphylococcal Biofilm Formation on Solid Orthopaedic Implant Materials: In Vitro Study
Hironobu Koseki,Akihiko Yonekura,Takayuki Shida,Itaru Yoda,Hidehiko Horiuchi,Yoshitomo Morinaga,Katsunori Yanagihara,Hideyuki Sakoda,Makoto Osaki,Masato Tomita +9 more
TL;DR: Results suggest that surface properties, such as hydrophobicity or the low surface free energy of Co-Cr-Mo, may have some influence in inhibiting or delaying the two-dimensional expansion of biofilm on surfaces with a similar degree of smoothness.
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Dexamethasone inhibition of TGFβ-induced cell growth and type II collagen mRNA expression through ERK-integrated AP-1 activity in cultured rat articular chondrocytes
Youichi Miyazaki,Tomoo Tsukazaki,Yasuhiro Hirota,Akihiko Yonekura,Makoto Osaki,Hiroyuki Shindo,Shunichi Yamashita +6 more
TL;DR: The results indicate that DEX suppressed TGF beta-induced chondrocyte proliferation and type II collagen expression, probably through selective inhibition of ERK integrated AP-1 activation.
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Primary human bone marrow adipocytes support TNF-α-induced osteoclast differentiation and function through RANKL expression
Hisataka Goto,Akira Hozumi,Makoto Osaki,Tatsuya Fukushima,Kazutaka Sakamoto,Akihiko Yonekura,Masato Tomita,Keizo Furukawa,Hiroyuki Shindo,Hideo Baba +9 more
TL;DR: Evaluating the effect of Tumor necrosis factor-alpha (TNF-α) on RANKL expression in bone marrow adipocytes, and osteoclast differentiation supported by human bone marrow fatocytes found TNF- α induced the ability of bone marrow lipidocytes to promote osteOClast differentiation and activity in a manner directly related to RankL expression.