A
Akihisa Abe
Researcher at Tokyo Medical University
Publications - 34
Citations - 5892
Akihisa Abe is an academic researcher from Tokyo Medical University. The author has contributed to research in topics: Apoptosis & Programmed cell death. The author has an hindex of 15, co-authored 34 publications receiving 5382 citations.
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The omega-hydroxy palmitic acid induced apoptosis in human lung carcinoma cell lines H596 and A549.
TL;DR: It is found that omega-hydroxy palmitic acid has both cell growth inhibiting and cell death inducing actions on human lung adenosquamous carcinoma cell line H596 and adenocarcinomas cell line A549, and it is thought that apoptotic cell death was related to caspase activity.
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Subcellular localization of docosahexaenoic acid and arachidonic acid ω-hydroxylation activity in the brain, liver and colonic adenocarcinoma
TL;DR: Results suggest that there is a difference regarding subcellular localization of the omega-hydroxylation activity depending on the species of the organs.
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High-performance liquid chromatography-thermospray mass spectrometry of ω-carboxyleukotriene B4 and ω-hydroxyleukotriene B4 from an incubation mixture of human colonic well-differentiated adenocarcinoma homogenate
Mototeru Yamane,Shinsuke Shimizu,Akihisa Abe,Hirokazu Sugiura,Masaaki Miyaoka,Toshihiko Saitoh +5 more
TL;DR: It is suggested that carcinoma cells themselves or leukocytes at the hostsite in a region of human colonic well-differentiated adenocarcinoma are performing omega-oxidation through NADPH-dependent omega-hydroxylation of leukotriene B4.
Journal ArticleDOI
High-performance liquid chromatography-thermospray mass spectrometry of 5,6-dihydroxyeicosatrienoate-1,5-lactone from tissue homogenates
Mototeru Yamane,Akihisa Abe +1 more
TL;DR: 5,6-DiHETriE-delta-lactone, corresponding to [20:4(n-6)], was shown to be characterized by a high intensity of quasimolecular ions (MH+ and MNH4+), using ion analysis obtained by reversed-phase HPLC-thermospray MS.