A
Akio Nomoto
Researcher at Central Institute for Experimental Animals
Publications - 4
Citations - 15
Akio Nomoto is an academic researcher from Central Institute for Experimental Animals. The author has contributed to research in topics: Poliovirus & Viral replication. The author has an hindex of 2, co-authored 4 publications receiving 15 citations.
Papers
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Book ChapterDOI
Molecular Mechanisms of Poliovirus Pathogenesis
Akio Nomoto,Satoshi Koike +1 more
TL;DR: Poliomyelitis, an acute disease of the central nervous system (CNS), is caused by poliovirus, a human enterovirus belonging to the Picornaviridae, and is classified into three stable serotypes (types 1, 2, and 3).
Patent
Method for examining neurovirulence of polio virus
Shinobu Abe,Yoshihiro Ota,So Hashizume,Satoshi Koike,Akio Nomoto,Hiromichi Yonekawa,Choji Taya,Tatsuji Nomura +7 more
TL;DR: In this article, a method of examining the neurovirulence of a polio virus was proposed, which consisted inoculating a vaccine-resistant version of the virus into the spinal cord of a transgenic mouse comprising a gene for a polio receptor.
Patent
Method of testing neurotoxicity of poliovirus vaccine
Shinobu Abe,Yoshihiro Ota,So Hashizume,Akio Nomoto,Hiromichi Yonekawa,Choji Taya,Tatsuji Nomura +6 more
TL;DR: In this paper, a method of testing the neurotoxicity of poliovirus vaccine by inoculating the vaccine into the spinal cord of a transgenic nonprimatial vertebrate having poliirus receptor genes introduced thereinto was proposed.
MouseCellFactors forStrand-Specific Initiation ofPoliovirus RNA Synthesis
TL;DR: Results indicate that a specific hostfactor(s) is involved in the efficient initiation process of positive-strand RNA synthesis of poliovirus and thirdly, that this hostfactor appeared tooccur only on the synthesis ofpositive- Strand RNA.