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Showing papers by "Alan Rozanski published in 1996"


Journal ArticleDOI
TL;DR: Tiggers of ischemia in patients with coronary artery disease during daily life include not only strenuous exercise, but also activities involving low levels of exertion, such as anger and smoking.

175 citations


Journal ArticleDOI
TL;DR: Results of automated GSPECT LV EF correlated well with those of manual G SPECT and gated first-pass and equilibrium blood pool values and were highly reproducible.

99 citations


Journal ArticleDOI
TL;DR: Exogenous factors (physical and mental activities) are most potent as triggers of ischemia during the morning hours, and the postural change after awakening contributes to the morning increase in ischemIA.
Abstract: Background The morning peak in myocardial ischemia has been related to diurnal variations in physical and mental activities and to postural changes upon awakening. This study assesses (1) the effects of exogenous activity triggers at different times of the day and (2) the contribution of an endogenous (ie, activity- and posture-independent) circadian vulnerability for ambulatory ischemia. Methods and Results Sixty-three stable coronary artery disease patients underwent ambulatory ECG monitoring and completed a structured diary assessing physical and mental activities. During 2519 hours of observation, a morning increase in ischemia coincided with increases in physical and mental activities, and an evening decrease in ischemia coincided with a decline in activities. During the morning, ischemic versus ischemia-free periods were more likely to occur with high levels of physical activity (P<.001). High physical activity triggered ischemia to a lesser but still significant extent (P<.05) in the afternoon but ...

95 citations


Journal ArticleDOI
TL;DR: In this article, the reproducibility of HRV measurements in patients with stable coronary artery disease (CAD) who have daily life myocardial ischemia was studied with two consecutive 24-hour Holter monitoring recordings.
Abstract: Heart rate variability (HRV) appears to be a strong predictor of death. The reproducibility of HRV measurements in patients with stable coronary artery disease (CAD) who have daily life myocardial ischemia, however, is unknown. Thirty patients with stable CAD (25 men and 5 women; aged 62 ± 8 years) with daily life ischemia were studied with 2 consecutive 24-hour Holter monitoring recordings. Intra- and interobserver reproducibility of the HRV measures was high, with correlations ranging from 0.990 to 0.999 (p

44 citations


Journal ArticleDOI
TL;DR: It is concluded that gender-related differences in left ventricular response to exercise are present in a wide range of patients referred for testing.

40 citations


Journal ArticleDOI
TL;DR: Of the various approaches being considered to limit the authors' cardiovascular health care expenditures, targeted secondary prevention of coronary disease may offer a solution for both limiting interventional cardiologic expenses and improving coronary disease patients' health.

12 citations