Showing papers by "Alan Rozanski published in 2001"
TL;DR: Half of the authors' CAD patients manifested diminution in PWA that was consistent with peripheral arterial vasoconstriction during the early phases of treadmill exercise, which may represent generalized vascular pathology secondary to atherosclerosis.
Abstract: Background—Peripheral cutaneous vascular beds, such as the fingertips, contain a high concentration of arteriovenous anastomoses, richly innervated by α-adrenergic nerve fibers, to control heat regulation. Nevertheless, for a variety of technical reasons, finger blood flow responses to exercise have not been well studied in health and disease. Hence, we compared finger pulse-wave amplitude (PWA) responses to exercise among 50 normal volunteers and 57 patients with atherosclerotic coronary artery disease (CAD) using a robust, modified form of volume plethysmography. Methods and Results—PWA was quantified for each minute of exercise as a ratio relative to baseline. Exercise PWA responses were compared with clinical, hemodynamic, ECG, and myocardial single photon emission computed tomography parameters. Among normal subjects, 38 (76%) manifested vasodilation throughout exercise and 12 (24%) manifested initial vasodilation followed by vasoconstriction at high heart rate thresholds. None manifested vasoconstri...
82 citations
TL;DR: The current role and new developments, with respect to the use of myocardial perfusion imaging, in determining patient risk for cardiac events and the cost-effective integration of such information into patient management decisions are addressed.
24 citations
TL;DR: The results underscore the importance of postexercise imaging in enhancing clinical assessment and imply that there are important technical considerations to contemplate when performing certain tests such as postex exercise echocardiography.
4 citations
TL;DR: Comparisons of stress-imaging procedures require analyses based on their 2 principal applications: diagnostic and prognostic assessments, and it is important to distinguish between a test's efficacy and its effectiveness.
3 citations
TL;DR: Important guiding principles, common to stress-imaging tests, are reviewed in this article.
1 citations