Showing papers by "Alan Rozanski published in 2017"
TL;DR: Randomization of hospitalized patients admitted for chest pain work-up to either CCTA or to stress testing resulted in similar discharge times, change in medical therapies at discharge, frequency of downstream noninvasive testing, and repeat hospitalizations.
32 citations
TL;DR: Deconditioning and inability to walk constituted the top two reasons for performing pharmacologic stress, followed by frailty, left bundle branch block (for MPI), resting wall motion abnormality (for echocardiography), and failed exercise attempts.
19 citations
TL;DR: In this article, a review of imaging-based screening for cardiovascular disease is presented, including analysis regarding the optimal methods for screening, and what are the relevant clinical outcomes to assess the efficacy of imaging based screening for prevention.
Abstract: The optimal approach for screening for cardiovascular disease remains controversial. A new standard of “therapeutic efficacy” requires that screening tests which involve cardiac imaging not only predict events but also improve clinical outcomes compared with usual care. To date, 5 prospective randomized trials have been conducted to compare outcomes based on imaging-guided screening and prevention versus assignment to usual care in screening populations. One trial involved cardiac stress imaging, 3 involved coronary artery calcium scanning, and 1 involved coronary computed tomography angiography. Due to the current very low event risk in asymptomatic populations, these trials have been substantially underpowered to assess the impact of imaging-guided prevention on hard cardiac events. This review derives lessons learned from these trials relative to the future design of imaging-based screening trials, including analysis regarding the optimal methods for screening, and what are the relevant clinical outcomes to assess the efficacy of imaging-based screening for prevention.
10 citations
TL;DR: Examination of the effect of HRT treatment on coronary artery calcium (CAC) and on mortality in a large retrospective cohort of post-menopausal women found it to be a cardio-protective agent.
4 citations
Journal Article•
TL;DR: Assessment of coronary artery calcium with non-contrast computed tomography is known to add to clinical risk assessment in prediction of atherosclerotic cardiovascular dise...
Abstract: Introduction: Assessment of coronary artery calcium (CAC) with non-contrast computed tomography (CT) is known to add to clinical risk assessment in prediction of atherosclerotic cardiovascular dise...
2 citations
TL;DR: Coronary artery calcium score is a marker of coronary atherosclerosis with increasing prevalence as a function of age; however, the prevalence and prognostic implications of CAC scanning in elderly patients are not well defined.
1 citations