A
Alan Yueh Luen Lee
Researcher at National Health Research Institutes
Publications - 1
Citations - 139
Alan Yueh Luen Lee is an academic researcher from National Health Research Institutes. The author has contributed to research in topics: Unfolded protein response & Neurodegeneration. The author has an hindex of 1, co-authored 1 publications receiving 74 citations.
Papers
More filters
Journal ArticleDOI
TDP-43 induces mitochondrial damage and activates the mitochondrial unfolded protein response
Peng Wang,Jianwen Deng,Jie Dong,Jianghong Liu,Eileen H. Bigio,M.-Marsel Mesulam,Tao Wang,Lei Sun,Li Wang,Alan Yueh Luen Lee,Warren A. McGee,Xiaoping Chen,Kazuo Fushimi,Li Zhu,Jane Y. Wu,Jane Y. Wu +15 more
TL;DR: It is suggested that blocking or reversing mitochondrial damage may provide a potential therapeutic approach to these devastating diseases and uncovered a previously unknown role of LonP1 in regulating mitochondrial TDP-43 levels, but also advanced the understanding of the pathogenic mechanisms for T DP-43 proteinopathy.