A
Albert J. Robichaud
Researcher at Bristol-Myers Squibb
Publications - 24
Citations - 975
Albert J. Robichaud is an academic researcher from Bristol-Myers Squibb. The author has contributed to research in topics: Tautomer & Receptor. The author has an hindex of 12, co-authored 24 publications receiving 934 citations. Previous affiliations of Albert J. Robichaud include New York City Law Department.
Papers
More filters
Journal Article
Possible role of valvular serotonin 5-HT(2B) receptors in the cardiopathy associated with fenfluramine.
Lawrence W. Fitzgerald,Timothy Burn,Barry S. Brown,John P. Patterson,Martha H. Corjay,Patricia A. Valentine,Jung-Hui Sun,John Link,Ilgar Abbaszade,Jeannine M. Hollis,Brian L. Largent,Paul R. Hartig,Gregory Hollis,Paul C. Meunier,Albert J. Robichaud,David Robertson +15 more
TL;DR: It is proposed that preferential stimulation of valvular 5-HT(2B) receptors by norfenfluramine, ergot drugs, or5-HT released from carcinoid tumors (with or without accompanying 5- HT(2A) receptor activation) may contribute to valvial fibroplasia in humans.
Patent
Substituted heterocycle fused gamma-carbolines
Albert J. Robichaud,Lee Taekyu,Wei Deng,Mitchell Ian S,Chen Wenting,Mcclung Christopher D,Calvello Emilie J B,Zawrotny David M +7 more
TL;DR: In this article, the authors proposed a structural Formula (I) or pharmaceutically acceptable salt forms thereof, wherein R?1, R5, R 6a, R6b, R7, R8, R9?, X, b, k, m, and n, and the dashed lines are described herein.
Journal ArticleDOI
Discovery of a Tetracyclic Quinoxaline Derivative as a Potent and Orally Active Multifunctional Drug Candidate for the Treatment of Neuropsychiatric and Neurological Disorders
Peng Li,Qiang Zhang,Albert J. Robichaud,Lee Taekyu,John Tomesch,Wei Yao,J. David Beard,Gretchen L. Snyder,Hongwen Zhu,Youyi Peng,Joseph P. Hendrick,Kimberly E. Vanover,Robert E. Davis,Sharon Mates,Lawrence P. Wennogle +14 more
TL;DR: The synthesis and structure-activity relationships of a class of tetracyclic butyrophenones that exhibit potent binding affinities to serotonin 5-HT(2A) and dopamine D2 receptors are reported, which led to the discovery of ITI-007, which is a potent 5- HT( 2A) antagonist, postsynaptic D2 antagonist, and inhibitor of serotonin transporter.
Patent
Substituted tricyclic gamma-carbolines as serotonin receptor agonists and antagonists
TL;DR: In this article, a structural formula (I): or a pharmaceutically acceptable salt thereof, wherein R?1, R4a, R5, R6, R7, R8, R9?, and m, are defined.
Patent
Substituted pyridoindoles as serotonin agonists and antagonists
TL;DR: In this paper, the authors proposed a structural Formula (I) or pharmaceutically acceptable salt forms thereof, wherein R1, R5, R6, R7, R8, R9, X, b, k, and n, and the dashed lines are described herein.