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Albert K. Beck
Researcher at ETH Zurich
Publications - 52
Citations - 1696
Albert K. Beck is an academic researcher from ETH Zurich. The author has contributed to research in topics: Enantioselective synthesis & Organocatalysis. The author has an hindex of 18, co-authored 52 publications receiving 1620 citations. Previous affiliations of Albert K. Beck include California Institute of Technology & University of Giessen.
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Journal ArticleDOI
Are Oxazolidinones Really Unproductive, Parasitic Species in Proline Catalysis? – Thoughts and Experiments Pointing to an Alternative View
Dieter Seebach,Albert K. Beck,D. Michael Badine,Michael Limbach,Albert Eschenmoser,Adi M. Treasurywala,Reinhard Hobi,Walter Prikoszovich,Bernard Linder +8 more
TL;DR: The N,O-acetal and N-O-ketal derivatives (oxazolidinones) formed from proline, and aldehydes or ketones are well-known today, and they are detectable in reaction mixtures involving proline catalysis, where they have been considered ‘parasitic dead ends’ as discussed by the authors.
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Enantio- and diastereoselective titanium-TADDOLate catalyzed addition of diethyl and bis(3-buten-1-yl) zinc to aldehydes a full account with preparative details
TL;DR: The TADDOLate method of adding dialkyl zinc reagents to aldehydes enantioselectively is compared with other Lewis acid or amino alcohol mediated methods.
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Isolation and X-Ray Structures of Reactive Intermediates of Organocatalysis with Diphenylprolinol Ethers and with Imidazolidinones
TL;DR: In this article, a 2D-NMR spectrum of the third iminium salt was recorded and the crystal and NMR structures confirmed the commonly accepted, general structures of the two types of reactive intermediates in organocatalysis with the five-membered heterocycles.
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Structures of the reactive intermediates in organocatalysis with diarylprolinol ethers
Uroš Grošelj,Dieter Seebach,D. Michael Badine,W. Bernd Schweizer,Albert K. Beck,Ingo Krossing,Petra Klose,Yujiro Hayashi,Tadafumi Uchimaru +8 more
TL;DR: In this article, the structure of the reactive intermediates (enamines and iminium ions) of organocatalysis with diarylprolinol derivatives have been determined by melting/decomposition points, [α]D, elemental analysis, IR and NMR spectroscopy, and high resolution mass spectrometry (HR-MS).
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Preparation and Structural Analysis of Several New α,α,α′,α′-Tetraaryl-1,3-dioxolane-4,5-dimethanols (TADDOL's) and TADDOL analogs, their evaluation as titanium ligands in the enantioselective addition of methyltitanium and diethylzinc reagents to benzaldehyde, and refinement of the mechanistic hypothesis
Yoshio N. Ito,Xavier Ariza,Albert K. Beck,Andrej Boháč,Camille Ganter,Robert E. Gawley,Florian N. M. Kühnle,Juraj Tuleja,Yan Ming Wang,Dieter Seebach +9 more
TL;DR: In this article, the authors used X-ray crystallography and molecular mechanics to analyze the structure of the TADDOL's and showed that a combination of structural features appear necessary for good catalytic efficiency and high selectivity.