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Albert Meyer

Researcher at University of Montpellier

Publications -  86
Citations -  1833

Albert Meyer is an academic researcher from University of Montpellier. The author has contributed to research in topics: Click chemistry & Phosphoramidite. The author has an hindex of 25, co-authored 86 publications receiving 1727 citations. Previous affiliations of Albert Meyer include Centre national de la recherche scientifique & Claude Bernard University Lyon 1.

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Fucosylated pentaerythrityl phosphodiester oligomers (PePOs): automated synthesis of DNA-based glycoclusters and binding to Pseudomonas aeruginosa lectin (PA-IIL).

TL;DR: The synthesis of propargylated pentaerythrityl phosphodiester oligomers (PePOs) was achieved using a DNA synthesizer with a bis-propargylator-based phosphoramidite and the IC50 values measured are 10-20 times better than for monovalent l-fucose and denotate for a "macromolecular" effect rather than a "cluster" effect.
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New strategies for cyclization and bicyclization of oligonucleotides by click chemistry assisted by microwaves.

TL;DR: The synthesis of cyclic, branched, and bicyclic oligonucleotides was performed by copper-catalyzed azide-alkyne cycloaddition assisted by microwaves in solution and on solid support to introduce alkyne and bromo functions into the same oligon nucleotide by solid-phase synthesis on a DNA synthesizer.
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Synthesis of Mannose and Galactose Oligonucleotide Conjugates by Bi-click chemistry

TL;DR: Glyco oligonucleotide conjugates, each exhibiting two mannose and two galactose residues, were efficiently synthesized by two successive 1,3-dipolar cycloadditions (click chemistry) using phosphoramidite derivatives.